SCHEMBL133176

SCHEMBL133176

CCn1c2ccccc2c2cc(/C=C/c3ccccc3)ccc21

nearest known ligand 0.65

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KDM4E B2RXH2 8/20 0.65
POLB P06746 4/20 0.65
HTT P42858 3/20 0.65
PKM P14618 1/20 0.65
SRC P12931 4/20 0.62
BCHE P06276 3/20 0.60
ACHE P22303 3/20 0.60
ALDH1A1 P00352 7/20 0.58
HPGD P15428 7/20 0.58
MAPT P10636 7/20 0.58
MEN1 O00255 7/20 0.58
KMT2A Q03164 7/20 0.58
HSD17B10 Q99714 2/20 0.58
MAPK1 P28482 2/20 0.58
HBB P68871 1/20 0.58
TDP1 Q9NUW8 1/20 0.58
LMNA P02545 7/20 0.58
SMN1; SMN2 Q16637 6/20 0.58
USP2 O75604 1/20 0.58
TSHR P16473 1/20 0.58

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL133177 1.00 KDM4E (0.65) KDM4EPOLBHTTPKMSRC
SCHEMBL3443606 0.97 KDM4E (0.68) KDM4EPOLBHTTPKMSRC
SCHEMBL29415213 0.97 KDM4E (0.68) KDM4EPOLBHTTPKMSRC
SCHEMBL29357702 0.97 KDM4E (0.68) KDM4EPOLBHTTPKMSRC
SCHEMBL85408 0.97 KDM4E (0.68) KDM4EPOLBHTTPKMSRC
SCHEMBL11351964 0.95 KDM4E (0.57) KDM4EPOLBHTTPKMSRC
SCHEMBL11351967 0.95 KDM4E (0.57) KDM4EPOLBHTTPKMSRC
SCHEMBL2622625 0.94 KDM4E (0.62) KDM4EPOLBHTTPKMSRC
SCHEMBL31281511 0.92 KDM4E (0.63) KDM4EPOLBHTTPKMSRC
SCHEMBL385469 0.92 KDM4E (0.63) KDM4EPOLBHTTPKMSRC

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 106 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-4596754-A Electroconductive support, photosensitive layer comprising azo pigment charge generating layer, charge transport layer, alkali soluble resin RICOH COMPANY, LTD. (JP) 1986-06-24 US claimed
CN-112602206-A Organic electroluminescent element 国立大学法人九州大学 2021-04-02 CN disclosed
US-9235146-B2 Photoconductor RICOH COMPANY, LTD. (JP) 2016-01-12 US disclosed
US-9040215-B2 Amine compound, electrophotographic photoconductor, image forming method, image forming apparatus, and process cartridge RICOH COMPANY, LTD. (JP) 2015-05-26 US disclosed
US-9005856-B2 Hydroxygallium porphyrazine derivative mixture and electrophotographic photoconductor RICOH COMPANY, LTD. (JP) 2015-04-14 US disclosed
US-20150079509-A1 PHOTOCONDUCTOR RICOH COMPANY, LTD. (JP) 2015-03-19 US disclosed
US-8889324-B2 Image bearing member, image forming method, image forming apparatus, and process cartridge RICOH COMPANY, LTD. (JP) 2014-11-18 US disclosed
US-8809543-B2 Electrophotographic photoreceptor, electrophotographic image forming method, electrophotographic image forming apparatus, and process cartridge for electrophotographic image forming apparatus RICOH COMPANY, LTD. (JP) 2014-08-19 US disclosed
US-8586270-B2 Electrophotographic photoconductor, electrophotographic method, and electrophotographic apparatus RICOH COMPANY, LTD. (JP) 2013-11-19 US disclosed
US-20130202994-A1 AMINE COMPOUND, ELECTROPHOTOGRAPHIC PHOTOCONDUCTOR, IMAGE FORMING METHOD, IMAGE FORMING APPARATUS, AND PROCESS CARTRIDGE RICOH COMPANY, LTD. (JP) 2013-08-08 US disclosed
US-4716220-A CHARGE CARRIER GENERATING MATERIALS RICOH CO., LTD. (JP) 1987-12-29 US disclosed
US-4708921-A Photosensitive material containing disazo compound for use in electrophotography RICOH CO., LTD. (JP) 1987-11-24 US disclosed
US-4702979-A ELECTROCONDUCTIVE CATHODE LAYER, PHOTOCONDUCTIVE LAYER OF CHARGE-GENERATING ORGANIC PIGMENT, ANODIC ION REACTION AT INTERFACE WHEN IRRADIATED RICOH CO., LTD. (JP) 1987-10-27 US disclosed
US-4672149-A PHOTOACTIVE LAYER CONTAINING A DISAZO PIGMENT; SOLAR CELLS; EFFICIENCY RICOH CO., LTD. (JP) 1987-06-09 US disclosed
US-4663442-A ELECTROGRAPHY, PHOTOSENSITIVITY RICOH CO., LTD. (JP) 1987-05-05 US disclosed
US-4619878-A Tetrazonium salt compound, disazo compound, method for preparing the same, and photosensitive material containing said disazo compound for use in electrophotography RICOH CO., LTD. (JP) 1986-10-28 US disclosed
US-4596754-A Electroconductive support, photosensitive layer comprising azo pigment charge generating layer, charge transport layer, alkali soluble resin RICOH COMPANY, LTD. (JP) 1986-06-24 US disclosed
US-4582771-A Disazo compound, method for preparing the same, and electrophotographic element containing the same for use in electrophotography RICOH CO., LTD. (JP) 1986-04-15 US disclosed
US-4565759-A PHOTOCONDUCTIVE LAYER ON ELECTROCONDUCTIVE SUPPORT RICOH CO., LTD. (JP) 1986-01-21 US disclosed
US-4540643-A Tetrazonium salt compounds, novel disazo compounds, method for the production thereof and disazo compound-containing electrophotographic elements RICOH CO., LTD. (JP) 1985-09-10 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20130202994-A1 AMINE COMPOUND, ELECTROPHOTOGRAPHIC PHOTOCONDUCTOR, IMAGE FORMING METHOD, IMAGE FORMING APPARATUS, AND PROCESS CARTRIDGE ARL1, ATXN2L, AHR KDM4E 4009/4885POLB 2553/4885HTT 1509/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.