⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL467875 | 0.71 | — | — | |
| SCHEMBL9851138 | 0.71 | — | — | |
| SCHEMBL1007444 | 0.71 | — | — | |
| SCHEMBL3094064 | 0.71 | — | — | |
| SCHEMBL1291808 | 0.71 | — | — | |
| SCHEMBL826807 | 0.71 | — | — | |
| SCHEMBL12829544 | 0.67 | — | — | |
| SCHEMBL15704217 | 0.67 | — | — | |
| SCHEMBL104811 | 0.66 | APP (0.32) | — | |
| SCHEMBL3723732 | 0.66 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1394 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2807170-B1 | PHRAGMALIN LIMONOIDS FOR THE TREATMENT OF SEXUAL DYSFUNCTION | DICOT AB (SE) | 2019-03-13 | — | — | EP | claimed |
| US-10112918-B2 | 15-oxospiramilactone derivatives, preparation method and uses thereof | KUNMING INSTITUTE OF BOTANY, THE CHINESE ACADEMY OF SCIENCES (CN) | 2018-10-30 | — | — | US | claimed |
| US-20160185743-A1 | 15-Oxospiramilactone Derivatives, Preparation Method and Uses Thereof | CENTER FOR EXCELLENCE IN MOLECULAR CELL SCIENCE, CHINESE ACADEMY OF SCIENCES (CN) | 2016-06-30 | — | — | US | claimed |
| US-20150072942-A1 | BORONIC ESTER AND ACID COMPOUNDS, SYNTHESIS AND USES | MILLENNIUM PHARMACEUTICALS, INC. (US) | 2015-03-12 | — | — | US | claimed |
| US-20150011616-A1 | PHRAGAMALIN LIMONOIDS FOR THE TREATMENT OF SEXUAL DYSFUNCTION | DICOT PHARMA AB (SE) | 2015-01-08 | — | — | US | claimed |
| CN-104254537-A | Phragmalin limonoids for the treatment of sexual dysfunction | DICOTYLEDON AB | 2014-12-31 | — | — | CN | claimed |
| US-8921336-B2 | Small molecule myristate inhibitors of BCR-ABL and methods of use | DANA-FARBER CANCER INSTITUTE, INC. (US) | 2014-12-30 | — | — | US | claimed |
| EP-2807170-A2 | PHRAGAMALIN LIMONOIDS FOR THE TREATMENT OF SEXUAL DYSFUNCTION | Dicotyledon AB (SE) | 2014-12-03 | — | — | EP | claimed |
| WO-2013110744-A2 | NOVEL COMPOUNDS, THEIR MANUFACTURE AND USES (II) | DICOTYLEDON AB (SE) | 2013-08-01 | — | — | WO | claimed |
| CN-101215276-B | N,N'-substituted phenylpropylamino acid phenylpropylaminoalcohols esters derivatives and preparation method thereof | UNIV SHENYANG PHARMACEUTICAL | 2013-05-15 | — | — | CN | claimed |
| EP-0082694-A2 | Herbicidal cyclohexane-1,3-dione derivatives | ICI AUSTRALIA LIMITED (AU) | 1983-06-29 | — | — | EP | claimed |
| EP-0080301-A2 | Herbicidal cyclohexane-1,3-dione derivatives | ICI AUSTRALIA LIMITED (AU) | 1983-06-01 | — | — | EP | claimed |
| EP-0024172-B1 | ANTITUMOR AND IMMUNOSUPPRESSIVE 4-CARBAMOYLIMIDAZOLIUM-5-OLATE DERIVATIVES, PHARMACEUTICAL COMPOSITION AND PRODUCTION THEREOF | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1983-05-11 | — | — | EP | claimed |
| US-4375470-A | 2(1-Piperazinyl)-cycloheptimidazole antihypertensive composition and methods | AMERICAN HOME PRODUCTS CORPORATION (US) | 1983-03-01 | — | — | US | claimed |
| US-4317825-A | WATER SOLUBILITY | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1982-03-02 | — | — | US | claimed |
| US-4293462-A | Process for the manufacture of enol derivatives, and intermediates | CIBA-GEIGY CORPORATION (US) | 1981-10-06 | — | — | US | claimed |
| US-4258188-A | HYPOTENSIVE AGENTS | AMERICAN HOME PRODUCTS CORPORATION (US) | 1981-03-24 | — | — | US | claimed |
| EP-0024172-A1 | Antitumor and immunosuppressive 4-carbamoylimidazolium-5-olate derivatives, pharmaceutical composition and production thereof | SUMITOMO CHEMICAL COMPANY, LIMITED (JP) | 1981-02-25 | — | — | EP | claimed |
| US-4250183-A | GASTOINTESTINAL DISORDERS; DISEASES OF THE PANCREAS, GALL BLADDER, AND LIVER | BYK GULDEN LOMBERG CHEMISCHE FABRIK GMBH (DE) | 1981-02-10 | — | — | US | claimed |
| US-4110533-A | PROCESS FOR THE MANUFACTURE OF ENOL DERIVATIVES | CIBA-GEIGY CORPORATION (US) | 1978-08-29 | — | — | US | claimed |