Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIM1 | P11309 | 13/20 | 0.76 |
| ▸ | CLK1 | P49759 | 1/20 | 0.62 |
| ▸ | DYRK2 | Q92630 | 1/20 | 0.62 |
| ▸ | MEN1 | O00255 | 6/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.55 |
| ▸ | MAPT | P10636 | 2/20 | 0.55 |
| ▸ | GAA | P10253 | 1/20 | 0.55 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.55 |
| ▸ | GFER | P55789 | 1/20 | 0.55 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.55 |
| ▸ | RAB9A | P51151 | 5/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | LMNA | P02545 | 1/20 | 0.52 |
| ▸ | TLR9 | Q9NR96 | 1/20 | 0.52 |
| ▸ | NPC1 | O15118 | 4/20 | 0.50 |
| ▸ | AGTR1 | P30556 | 1/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.50 |
| ▸ | ATM | Q13315 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2834464 | 0.91 | PIM1 (0.66) | PIM1CLK1DYRK2MEN1KMT2A | |
| SCHEMBL2834470 | 0.91 | PIM1 (0.66) | PIM1CLK1DYRK2MEN1KMT2A | |
| SCHEMBL14115818 | 0.86 | PIM1 (1.00) | PIM1CLK1DYRK2MEN1KMT2A | |
| SCHEMBL4934423 | 0.86 | PIM1 (1.00) | PIM1CLK1DYRK2MEN1KMT2A | |
| SCHEMBL29696924 | 0.86 | PIM1 (1.00) | PIM1CLK1DYRK2MEN1KMT2A | |
| SCHEMBL2835681 | 0.81 | PIM1 (0.60) | PIM1CLK1DYRK2MEN1KMT2A | |
| SCHEMBL2835672 | 0.81 | PIM1 (0.60) | PIM1CLK1DYRK2MEN1KMT2A | |
| SCHEMBL2834478 | 0.80 | PIM1 (0.69) | PIM1CLK1DYRK2MEN1KMT2A | |
| SCHEMBL2834480 | 0.80 | PIM1 (0.69) | PIM1CLK1DYRK2MEN1KMT2A | |
| SCHEMBL2836712 | 0.80 | PIM1 (0.60) | PIM1CLK1DYRK2MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100120847-A1 | STYRYLQUINOLINES, THEIR PROCESS OF PREPARATION AND THEIR THERAPEUTIC USES | BIOALLIANCE PHARMA (FR) | 2010-05-13 | — | — | US | disclosed |
| US-20100120847-A1 | STYRYLQUINOLINES, THEIR PROCESS OF PREPARATION AND THEIR THERAPEUTIC USES | BIOALLIANCE PHARMA (FR) | 2010-05-13 | — | — | US | disclosed |
| EP-2147912-A1 | Styrylquinolines, their process of preparation and their therapeutic uses | BioAlliance Pharma (FR) | 2010-01-27 | — | — | EP | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100120847-A1 | STYRYLQUINOLINES, THEIR PROCESS OF PREPARATION AND THEIR THERAPEUTIC USES | POLQ, PARP1, PARP14 | PIM1 19/4885CLK1 1817/4885DYRK2 2284/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.