Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPAR3 | Q9UBY5 | 10/20 | 0.45 |
| ▸ | LPAR2 | Q9HBW0 | 6/20 | 0.45 |
| ▸ | LPAR1 | Q92633 | 6/20 | 0.45 |
| ▸ | LPAR5 | Q9H1C0 | 1/20 | 0.36 |
| ▸ | SAT1 | P21673 | 1/20 | 0.36 |
| ▸ | SMPD1 | P17405 | 2/20 | 0.31 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 1/20 | 0.31 |
| ▸ | S1PR4 | O95977 | 2/20 | 0.30 |
| ▸ | S1PR1 | P21453 | 2/20 | 0.30 |
| ▸ | S1PR3 | Q99500 | 2/20 | 0.30 |
| ▸ | S1PR5 | Q9H228 | 2/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13322498 | 0.99 | LPAR3 (0.44) | LPAR3LPAR2LPAR1LPAR5SAT1 | |
| SCHEMBL13322495 | 0.96 | LPAR3 (0.40) | LPAR3LPAR2LPAR1LPAR5SAT1 | |
| SCHEMBL13322492 | 0.94 | LPAR3 (0.40) | LPAR3LPAR2LPAR1LPAR5SAT1 | |
| SCHEMBL13322502 | 0.92 | LPAR3 (0.49) | LPAR3LPAR2LPAR1LPAR5SAT1 | |
| SCHEMBL3051003 | 0.92 | LPAR3 (0.49) | LPAR3LPAR2LPAR1LPAR5SMPD1 | |
| SCHEMBL13322507 | 0.91 | LPAR3 (0.47) | LPAR3LPAR2LPAR1LPAR5SAT1 | |
| SCHEMBL13322504 | 0.91 | LPAR3 (0.47) | LPAR3LPAR2LPAR1LPAR5SAT1 | |
| SCHEMBL3048183 | 0.91 | LPAR3 (0.47) | LPAR3LPAR2LPAR1LPAR5SMPD1 | |
| SCHEMBL13322499 | 0.90 | LPAR3 (0.46) | LPAR3LPAR2LPAR1LPAR5SAT1 | |
| SCHEMBL3039226 | 0.89 | LPAR3 (0.55) | LPAR3LPAR2LPAR1LPAR5SMPD1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7709515-B2 | Compositions comprising ether compounds and pharmaceutical uses therefor | ESPERION THERAPEUTICS, INC. (US) | 2010-05-04 | — | — | US | disclosed |