Predicted protein targets (top 8)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPAR3 | Q9UBY5 | 10/20 | 0.42 |
| ▸ | LPAR2 | Q9HBW0 | 6/20 | 0.42 |
| ▸ | LPAR1 | Q92633 | 6/20 | 0.42 |
| ▸ | SAT1 | P21673 | 1/20 | 0.36 |
| ▸ | LPAR5 | Q9H1C0 | 1/20 | 0.34 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.30 |
| ▸ | CPT2 | P23786 | 1/20 | 0.30 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13322569 | 0.98 | LPAR3 (0.43) | LPAR3LPAR2LPAR1SAT1LPAR5 | |
| SCHEMBL13322565 | 0.97 | LPAR3 (0.41) | LPAR3LPAR2LPAR1SAT1LPAR5 | |
| SCHEMBL13322571 | 0.97 | LPAR3 (0.44) | LPAR3LPAR2LPAR1SAT1LPAR5 | |
| SCHEMBL13322584 | 0.97 | LPAR3 (0.44) | LPAR3LPAR2LPAR1SAT1LPAR5 | |
| SCHEMBL13322582 | 0.95 | LPAR3 (0.46) | LPAR3LPAR2LPAR1SAT1LPAR5 | |
| SCHEMBL3041746 | 0.94 | LPAR3 (0.47) | LPAR3LPAR2LPAR1LPAR5FFAR1 | |
| SCHEMBL3049272 | 0.92 | LPAR3 (0.48) | LPAR3LPAR2LPAR1LPAR5FFAR1 | |
| SCHEMBL3035022 | 0.91 | LPAR3 (0.50) | LPAR3LPAR2LPAR1LPAR5FFAR1 | |
| SCHEMBL3042655 | 0.91 | LPAR3 (0.50) | LPAR3LPAR2LPAR1LPAR5FFAR1 | |
| SCHEMBL3046776 | 0.91 | LPAR3 (0.46) | LPAR3LPAR2LPAR1LPAR5FFAR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7709515-B2 | Compositions comprising ether compounds and pharmaceutical uses therefor | ESPERION THERAPEUTICS, INC. (US) | 2010-05-04 | — | — | US | disclosed |