Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS1 | P23219 | 1/20 | 0.58 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.58 |
| ▸ | VNN1 | O95497 | 13/20 | 0.51 |
| ▸ | ZDHHC20 | Q5W0Z9 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL24093831 | 1.00 | PTGS1 (0.58) | PTGS1KCNH2VNN1ZDHHC20ALDH1A1 | |
| SCHEMBL18812079 | 1.00 | PTGS1 (0.58) | PTGS1KCNH2VNN1ZDHHC20ALDH1A1 | |
| SCHEMBL6465187 | 0.91 | PTGS1 (0.69) | PTGS1KCNH2VNN1ALDH1A1 | |
| SCHEMBL7042139 | 0.91 | PTGS1 (0.69) | PTGS1KCNH2VNN1ALDH1A1 | |
| Cysteamine SCHEMBL28277508 | 0.89 | PTGS1 (0.52) | PTGS1KCNH2VNN1ZDHHC20 | |
| SCHEMBL29930601 | 0.88 | PTGS1 (0.66) | PTGS1KCNH2VNN1ZDHHC20ALDH1A1 | |
| SCHEMBL15669344 | 0.86 | PTGS1 (0.50) | PTGS1KCNH2VNN1ZDHHC20ALDH1A1 | |
| SCHEMBL15669343 | 0.86 | PTGS1 (0.50) | PTGS1KCNH2VNN1ZDHHC20ALDH1A1 | |
| SCHEMBL16837041 | 0.86 | PTGS1 (0.59) | PTGS1KCNH2VNN1ZDHHC20ALDH1A1 | |
| SCHEMBL12572828 | 0.86 | PTGS1 (0.59) | PTGS1KCNH2VNN1ZDHHC20ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2753702-B1 | CELL-FREE PREPARATION OF CARBAPENEMS | GREENLIGHT BIOSCIENCES INC (US) | 2021-12-15 | — | — | EP | disclosed |
| EP-3753578-A1 | CYTOTOXIC PEPTIDES AND CONJUGATES THEREOF | Novartis AG (CH) | 2020-12-23 | — | — | EP | disclosed |
| US-7727738-B2 | Methods for generating analogs of coenzyme A | THE REGENTS OF THE UNIVERSITY OF CALIFORNIA (US) | 2010-06-01 | — | — | US | disclosed |
| US-20070128683-A1 | Metabolic delivery of coenzyme A analogs | NATIONAL SCIENCE FOUNDATION | 2007-06-07 | — | — | US | disclosed |