Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.61 |
| ▸ | TOP2A | P11388 | 14/20 | 0.48 |
| ▸ | TOP2B | Q02880 | 10/20 | 0.48 |
| ▸ | TOP1 | P11387 | 3/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.44 |
| ▸ | HPGD | P15428 | 2/20 | 0.44 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.44 |
| ▸ | ALB | P02768 | 1/20 | 0.44 |
| ▸ | HRH3 | Q9Y5N1 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3285735 | 0.95 | KDM4E (0.65) | KDM4ETOP2ATOP2BTOP1ALDH1A1 | |
| SCHEMBL13326835 | 0.90 | KDM4E (0.60) | KDM4ETOP2ATOP2BTOP1ALDH1A1 | |
| SCHEMBL13326535 | 0.90 | KDM4E (0.60) | KDM4ETOP2ATOP2BTOP1ALDH1A1 | |
| SCHEMBL13326846 | 0.90 | KDM4E (0.60) | KDM4ETOP2ATOP2BTOP1ALDH1A1 | |
| SCHEMBL3285229 | 0.90 | KDM4E (0.60) | KDM4ETOP2ATOP2BTOP1ALDH1A1 | |
| SCHEMBL3291611 | 0.88 | KDM4E (0.58) | KDM4ETOP2ATOP2BALDH1A1HPGD | |
| SCHEMBL13326598 | 0.87 | KDM4E (0.62) | KDM4ETOP2ATOP2BTOP1ALDH1A1 | |
| SCHEMBL3284348 | 0.87 | KDM4E (0.62) | KDM4ETOP2ATOP2BTOP1ALDH1A1 | |
| SCHEMBL3284385 | 0.86 | KDM4E (0.60) | KDM4ETOP2ATOP2BTOP1ALDH1A1 | |
| SCHEMBL3285671 | 0.86 | KDM4E (0.60) | KDM4ETOP2ATOP2BTOP1ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7713965-B2 | 7-substituted 3-carboxy-oxadiazino-quinolone derivatives, their preparation and their application as anti-bacterials | VETOQUINOL SA (FR) | 2010-05-11 | — | — | US | disclosed |
| US-7713965-B2 | 7-substituted 3-carboxy-oxadiazino-quinolone derivatives, their preparation and their application as anti-bacterials | VETOQUINOL SA (FR) | 2010-05-11 | — | — | US | disclosed |
| US-20090221565-A1 | NOVEL 7-SUBSTITUTED 3-CARBOXY-OXADIAZINO-QUINOLONE DERIVATIVES, THEIR PREPARATION AND THEIR APPLICATION AS ANTI-BACTERIALS | VETOQUINOL SA (FR) | 2009-09-03 | — | — | US | disclosed |
| US-20090221565-A1 | NOVEL 7-SUBSTITUTED 3-CARBOXY-OXADIAZINO-QUINOLONE DERIVATIVES, THEIR PREPARATION AND THEIR APPLICATION AS ANTI-BACTERIALS | VETOQUINOL SA (FR) | 2009-09-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20090221565-A1 | NOVEL 7-SUBSTITUTED 3-CARBOXY-OXADIAZINO-QUINOLONE DERIVATIVES, THEIR PREPARATION AND THEIR APPLICATION AS ANTI-BACTERIALS | CBR3, CBR1, TECR | KDM4E 3748/4885TOP2A 532/4885TOP2B 523/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.