Sugi Predict

Sugi Predict / Compounds / SCHEMBL13326545

SCHEMBL13326545

SCHEMBL13326545

Cc1nnc(NC2CCN(c3c(F)cc4c(=O)c(C(=O)O)cn5c4c3OCN5C)C2)o1

nearest known ligand 0.61

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
▸ KDM4E B2RXH2 4/20 0.61
▸ ALDH1A1 P00352 2/20 0.44
▸ HPGD P15428 2/20 0.44
▸ HSD17B10 Q99714 2/20 0.44
▸ ALB P02768 1/20 0.44
▸ HRH3 Q9Y5N1 1/20 0.44
▸ TUBB4A P04350 1/20 0.43
▸ POLB P06746 1/20 0.43
▸ TUBB P07437 1/20 0.43
▸ TUBA3C P0DPH7 1/20 0.43
▸ TUBA1B P68363 1/20 0.43
▸ TUBA4A P68366 1/20 0.43
▸ TUBB4B P68371 1/20 0.43
▸ TUBB3 Q13509 1/20 0.43
▸ TUBB2A Q13885 1/20 0.43
▸ TUBB8 Q3ZCM7 1/20 0.43
▸ TUBA3E Q6PEY2 1/20 0.43
▸ TUBA1A Q71U36 1/20 0.43
▸ SLC47A1 Q96FL8 1/20 0.43
▸ TUBA1C Q9BQE3 1/20 0.43

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13326523 0.88 KDM4E (0.59) KDM4EALDH1A1HPGDHSD17B10ALB
SCHEMBL3287162 0.88 KDM4E (0.59) KDM4EALDH1A1HPGDHSD17B10ALB
SCHEMBL10565230 0.86 KDM4E (0.71) KDM4EALDH1A1HPGDHSD17B10ALB
SCHEMBL13326593 0.86 KDM4E (0.62) KDM4EALDH1A1HPGDHSD17B10ALB
SCHEMBL3284170 0.86 KDM4E (0.62) KDM4EALDH1A1HPGDHSD17B10ALB
SCHEMBL3284348 0.86 KDM4E (0.62) KDM4EALDH1A1HPGDHSD17B10ALB
SCHEMBL3284985 0.86 KDM4E (0.62) KDM4EALDH1A1HPGDHSD17B10ALB
SCHEMBL13326598 0.86 KDM4E (0.62) KDM4EALDH1A1HPGDHSD17B10ALB
SCHEMBL3284223 0.86 KDM4E (0.62) KDM4EALDH1A1HPGDHSD17B10ALB
SCHEMBL13326588 0.84 KDM4E (0.60) KDM4EALDH1A1HPGDHSD17B10ALB

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-7713965-B2 7-substituted 3-carboxy-oxadiazino-quinolone derivatives, their preparation and their application as anti-bacterials VETOQUINOL SA (FR) 2010-05-11 — — US disclosed
US-7713965-B2 7-substituted 3-carboxy-oxadiazino-quinolone derivatives, their preparation and their application as anti-bacterials VETOQUINOL SA (FR) 2010-05-11 — — US disclosed
US-20090221565-A1 NOVEL 7-SUBSTITUTED 3-CARBOXY-OXADIAZINO-QUINOLONE DERIVATIVES, THEIR PREPARATION AND THEIR APPLICATION AS ANTI-BACTERIALS VETOQUINOL SA (FR) 2009-09-03 — — US disclosed
US-20090221565-A1 NOVEL 7-SUBSTITUTED 3-CARBOXY-OXADIAZINO-QUINOLONE DERIVATIVES, THEIR PREPARATION AND THEIR APPLICATION AS ANTI-BACTERIALS VETOQUINOL SA (FR) 2009-09-03 — — US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20090221565-A1 NOVEL 7-SUBSTITUTED 3-CARBOXY-OXADIAZINO-QUINOLONE DERIVATIVES, THEIR PREPARATION AND THEIR APPLICATION AS ANTI-BACTERIALS CBR3, CBR1, TECR KDM4E 3748/4885ALDH1A1 1998/4885HPGD 1022/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.