Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACACB | O00763 | 11/20 | 0.41 |
| ▸ | ACACA | Q13085 | 11/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.37 |
| ▸ | THRB | P10828 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 2/20 | 0.32 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13070822 | 0.91 | ACACB (0.48) | ACACBACACA | |
| SCHEMBL13096248 | 0.90 | ACACB (0.39) | ACACBACACAALDH1A1THRBHTT | |
| SCHEMBL12724985 | 0.89 | ACACB (0.46) | ACACBACACAKDM4EALDH1A1 | |
| SCHEMBL13071296 | 0.89 | ACACB (0.42) | ACACBACACA | |
| SCHEMBL13070875 | 0.88 | ACACB (0.37) | ACACBACACAALDH1A1HTTMAPK1 | |
| SCHEMBL13255226 | 0.88 | ACACB (0.39) | ACACBACACA | |
| SCHEMBL14290138 | 0.87 | ACACB (0.40) | ACACBACACATHRBHTTL3MBTL1 | |
| SCHEMBL14129223 | 0.82 | ACACB (0.45) | ACACBACACATSHR | |
| SCHEMBL13096250 | 0.82 | ACACB (0.50) | ACACBACACA | |
| SCHEMBL13070828 | 0.81 | KMT2A (0.33) | ACACBACACAALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7718186-B2 | 2-alkoxy-6-alkylphenyl-substituted spirocyclic tetramic acid derivatives | BAYER CROPSCIENCE AG (DE) | 2010-05-18 | — | — | US | disclosed |