Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 16/20 | 0.41 |
| ▸ | HTR2A | P28223 | 15/20 | 0.41 |
| ▸ | HTR2B | P41595 | 15/20 | 0.41 |
| ▸ | P2RX7 | Q99572 | 3/20 | 0.33 |
| ▸ | PARP1 | P09874 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10218602 | 0.95 | HTR2C (0.47) | HTR2CHTR2AHTR2BP2RX7PARP1 | |
| SCHEMBL10218003 | 0.80 | HTR2C (0.48) | HTR2CHTR2AHTR2BP2RX7 | |
| SCHEMBL10218600 | 0.75 | HTR2C (0.52) | HTR2CHTR2AHTR2B | |
| SCHEMBL10218080 | 0.74 | HTR2C (0.48) | HTR2CHTR2AHTR2B | |
| SCHEMBL10218608 | 0.72 | HTR2C (0.48) | HTR2CHTR2AHTR2B | |
| SCHEMBL10218597 | 0.72 | HTR2C (0.58) | HTR2CHTR2AHTR2B | |
| SCHEMBL10218617 | 0.72 | HTR2C (0.57) | HTR2CHTR2AHTR2B | |
| SCHEMBL10218610 | 0.71 | HTR2C (0.53) | HTR2CHTR2AHTR2B | |
| SCHEMBL10218604 | 0.70 | HTR2C (0.52) | HTR2CHTR2AHTR2B | |
| SCHEMBL10218613 | 0.70 | HTR2C (0.64) | HTR2CHTR2AHTR2B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010060952-A1 | 6,7,8,9-TETRAHYDRO-5H-1,4,7,10A-TETRAAZA-CYCLOHEPT[F]INDENE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THESE COMPOUNDS, THEIR USE AND PROCESSES FOR PREPARING THEM | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2010-06-03 | — | — | WO | disclosed |