Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR2C | P28335 | 18/20 | 0.68 |
| ▸ | HTR2B | P41595 | 17/20 | 0.68 |
| ▸ | HTR2A | P28223 | 16/20 | 0.68 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10218921 | 0.94 | HTR2C (0.77) | HTR2CHTR2BHTR2A | |
| SCHEMBL13329063 | 0.84 | HTR2C (0.62) | HTR2CHTR2BHTR2A | |
| SCHEMBL13329044 | 0.83 | HTR2C (0.73) | HTR2CHTR2BHTR2A | |
| SCHEMBL10218997 | 0.83 | HTR2C (0.85) | HTR2CHTR2BHTR2A | |
| SCHEMBL13329045 | 0.83 | HTR2C (0.60) | HTR2CHTR2BHTR2A | |
| SCHEMBL13329439 | 0.82 | HTR2C (0.89) | HTR2CHTR2BHTR2A | |
| SCHEMBL10219024 | 0.82 | HTR2C (0.76) | HTR2CHTR2BHTR2A | |
| SCHEMBL10219020 | 0.82 | HTR2C (0.83) | HTR2CHTR2BHTR2A | |
| SCHEMBL10216820 | 0.81 | HTR2C (1.00) | HTR2CHTR2BHTR2A | |
| SCHEMBL10216793 | 0.81 | HTR2C (1.00) | HTR2CHTR2BHTR2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010060952-A1 | 6,7,8,9-TETRAHYDRO-5H-1,4,7,10A-TETRAAZA-CYCLOHEPT[F]INDENE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS CONTAINING THESE COMPOUNDS, THEIR USE AND PROCESSES FOR PREPARING THEM | BOEHRINGER INGELHEIM INTERNATIONAL GMBH (DE) | 2010-06-03 | — | — | WO | disclosed |