Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CNR1 | P21554 | 11/20 | 0.57 |
| ▸ | PTGDR2 | Q9Y5Y4 | 9/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 2/20 | 0.41 |
| ▸ | CNR2 | P34972 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13329679 | 0.83 | CNR1 (0.58) | CNR1KCNH2CNR2 | |
| SCHEMBL13329706 | 0.80 | PTGDR2 (0.56) | CNR1PTGDR2 | |
| SCHEMBL13329687 | 0.79 | CNR1 (0.65) | CNR1KCNH2CNR2 | |
| SCHEMBL13329701 | 0.77 | CNR1 (0.63) | CNR1KCNH2CNR2 | |
| SCHEMBL13329686 | 0.76 | CNR1 (0.59) | CNR1KCNH2CNR2 | |
| SCHEMBL13329668 | 0.75 | CNR1 (0.57) | CNR1PTGDR2CNR2 | |
| SCHEMBL3305705 | 0.73 | CNR1 (1.00) | CNR1KCNH2CNR2 | |
| SCHEMBL13329678 | 0.71 | CNR1 (0.57) | CNR1KCNH2CNR2 | |
| SCHEMBL3314883 | 0.69 | PTGDR2 (0.42) | PTGDR2 | |
| SCHEMBL3316188 | 0.69 | CNR1 (0.56) | CNR1KCNH2CNR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100113502-A1 | Novel Tetrahydro-1H-Pyrido[4,3-b] Indole Derivatives as CB1 Receptor Ligands | ASTRAZENECA AB (SE) | 2010-05-06 | — | — | US | disclosed |
| US-20100113502-A1 | Novel Tetrahydro-1H-Pyrido[4,3-b] Indole Derivatives as CB1 Receptor Ligands | ASTRAZENECA AB (SE) | 2010-05-06 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100113502-A1 | Novel Tetrahydro-1H-Pyrido[4,3-b] Indole Derivatives as CB1 Receptor Ligands | CNR1, CNR2, OPRL1 | CNR1 1/4885PTGDR2 93/4885KCNH2 856/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.