Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HSP90AA1 | P07900 | 11/20 | 0.69 |
| ▸ | HSP90AB1 | P08238 | 3/20 | 0.62 |
| ▸ | F10 | P00742 | 4/20 | 0.40 |
| ▸ | LRRK2 | Q5S007 | 1/20 | 0.40 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.39 |
| ▸ | FEN1 | P39748 | 1/20 | 0.39 |
| ▸ | PRMT5 | O14744 | 1/20 | 0.36 |
| ▸ | WDR77 | Q9BQA1 | 1/20 | 0.36 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.36 |
| ▸ | HTT | P42858 | 1/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.36 |
| ▸ | ATR | Q13535 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2333467 | 0.91 | HSP90AA1 (0.71) | HSP90AA1HSP90AB1F10ALOX5APFEN1 | |
| SCHEMBL2329851 | 0.91 | HSP90AA1 (0.71) | HSP90AA1HSP90AB1F10ALOX5APFEN1 | |
| SCHEMBL13144782 | 0.91 | HSP90AA1 (0.71) | HSP90AA1HSP90AB1F10KDM4EHTT | |
| SCHEMBL2329817 | 0.90 | HSP90AA1 (0.69) | HSP90AA1HSP90AB1F10KDM4EHTT | |
| SCHEMBL2511442 | 0.90 | HSP90AA1 (0.66) | HSP90AA1HSP90AB1F10ALOX5APFEN1 | |
| SCHEMBL12199666 | 0.90 | HSP90AA1 (0.66) | HSP90AA1HSP90AB1F10ALOX5APFEN1 | |
| SCHEMBL3097085 | 0.89 | HSP90AA1 (0.63) | HSP90AA1HSP90AB1ALOX5APFEN1 | |
| SCHEMBL2330286 | 0.89 | HSP90AA1 (0.65) | HSP90AA1HSP90AB1ALOX5APFEN1 | |
| SCHEMBL2512041 | 0.88 | HSP90AA1 (0.64) | HSP90AA1HSP90AB1F10ALOX5APFEN1 | |
| SCHEMBL2510038 | 0.87 | HSP90AA1 (0.66) | HSP90AA1HSP90AB1F10ALOX5APFEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010066324-A1 | QUINAZOLINAMIDE DERIVATIVES | MERCK PATENT GMBH (DE) | 2010-06-17 | — | — | WO | disclosed |