Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 2/20 | 0.55 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.55 |
| ▸ | PKM | P14618 | 2/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.50 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | MAPT | P10636 | 3/20 | 0.50 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.50 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.50 |
| ▸ | GAA | P10253 | 2/20 | 0.50 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | TP53 | P04637 | 1/20 | 0.50 |
| ▸ | GFER | P55789 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.46 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.46 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13002249 | 1.00 | HTT (0.55) | HTTSMN1; SMN2PKMALDH1A1LMNA | |
| SCHEMBL8766382 | 1.00 | HTT (0.55) | HTTSMN1; SMN2PKMALDH1A1LMNA | |
| SCHEMBL12857630 | 1.00 | HTT (0.55) | HTTSMN1; SMN2PKMALDH1A1LMNA | |
| SCHEMBL13155587 | 1.00 | HTT (0.55) | HTTSMN1; SMN2PKMALDH1A1LMNA | |
| SCHEMBL13002250 | 1.00 | HTT (0.55) | HTTSMN1; SMN2PKMALDH1A1LMNA | |
| SCHEMBL10034459 | 0.96 | HTT (0.59) | HTTSMN1; SMN2PKMALDH1A1LMNA | |
| SCHEMBL12242069 | 0.96 | HTT (0.59) | HTTSMN1; SMN2PKMALDH1A1LMNA | |
| SCHEMBL15760412 | 0.96 | HTT (0.59) | HTTSMN1; SMN2PKMALDH1A1LMNA | |
| SCHEMBL13021062 | 0.96 | HTT (0.59) | HTTSMN1; SMN2PKMALDH1A1LMNA | |
| SCHEMBL13297321 | 0.93 | HTT (0.53) | HTTSMN1; SMN2PKMALDH1A1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100113688-A1 | High temperature melt processable semi-crystalline poly (aryl ether ketone) containing a (4-hydroxyphenyl) phthalazin-1 (2H)-one comonomer unit | POLYMICS, LTD. | 2010-05-06 | — | — | US | disclosed |