Predicted protein targets (top 5)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TNIK | Q9UKE5 | 18/20 | 0.69 |
| ▸ | TP53 | P04637 | 2/20 | 0.56 |
| ▸ | MAPT | P10636 | 2/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | POLB | P06746 | 1/20 | 0.56 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3396902 | 1.00 | TNIK (0.69) | TNIKTP53MAPTLMNAPOLB | |
| SCHEMBL3390562 | 0.94 | TNIK (0.67) | TNIKTP53MAPTLMNAPOLB | |
| SCHEMBL3394774 | 0.94 | TNIK (0.67) | TNIKTP53MAPTLMNAPOLB | |
| SCHEMBL3398128 | 0.92 | TNIK (0.77) | TNIKTP53MAPTLMNAPOLB | |
| SCHEMBL3434372 | 0.91 | TNIK (0.63) | TNIKTP53MAPTLMNAPOLB | |
| SCHEMBL3393218 | 0.89 | TNIK (0.73) | TNIKTP53MAPTLMNAPOLB | |
| SCHEMBL3396333 | 0.89 | TNIK (0.86) | TNIKTP53MAPTLMNAPOLB | |
| SCHEMBL3396885 | 0.89 | TNIK (0.68) | TNIKTP53MAPTLMNAPOLB | |
| SCHEMBL2366707 | 0.88 | TNIK (0.62) | TNIKTP53MAPT | |
| SCHEMBL3393893 | 0.88 | TNIK (0.67) | TNIKTP53MAPTLMNAPOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010064111-A1 | TNIK INHIBITOR AND THE USE | YAMADA TESSHI (JP) | 2010-06-10 | — | — | WO | disclosed |