Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BACE1 | P56817 | 20/20 | 0.80 |
| ▸ | CTSD | P07339 | 3/20 | 0.80 |
| ▸ | BACE2 | Q9Y5Z0 | 3/20 | 0.69 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3352151 | 0.97 | BACE1 (0.85) | BACE1CTSDBACE2 | |
| SCHEMBL13307090 | 0.97 | BACE1 (0.85) | BACE1CTSDBACE2 | |
| SCHEMBL13333991 | 0.95 | BACE1 (0.81) | BACE1CTSDBACE2 | |
| SCHEMBL13307088 | 0.92 | BACE1 (0.85) | BACE1CTSDBACE2 | |
| SCHEMBL3348136 | 0.92 | BACE1 (0.85) | BACE1CTSDBACE2 | |
| SCHEMBL3356787 | 0.92 | BACE1 (0.94) | BACE1CTSDBACE2 | |
| SCHEMBL14424676 | 0.90 | BACE1 (0.84) | BACE1CTSDBACE2 | |
| SCHEMBL3349892 | 0.90 | BACE1 (0.84) | BACE1CTSDBACE2 | |
| SCHEMBL3353630 | 0.90 | BACE1 (0.83) | BACE1CTSDBACE2 | |
| SCHEMBL13307338 | 0.90 | BACE1 (0.83) | BACE1CTSDBACE2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7727997-B2 | N,N′-substituted-1,3-diamino-2-hydroxypropane derivatives | ELAN PHARMACEUTICALS, INC. (US) | 2010-06-01 | — | — | US | disclosed |