SCHEMBL13337679

SCHEMBL13337679

CCc1ccc(Nc2nc(-c3ccc4scnc4c3)cn3ccnc23)cc1OC

nearest known ligand 0.59

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
SYK P43405 20/20 0.59
CD63 P08962 2/20 0.56

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL12016084 0.93 SYK (0.58) SYKCD63
SCHEMBL2524412 0.91 SYK (0.71) SYKCD63
SCHEMBL2478946 0.90 SYK (0.64) SYKCD63
SCHEMBL19503278 0.86 SYK (0.61) SYKCD63
SCHEMBL13337415 0.84 SYK (0.71) SYKCD63
SCHEMBL2482722 0.84 SYK (0.71) SYKCD63
SCHEMBL13337418 0.83 SYK (0.64) SYKCD63
SCHEMBL2484485 0.83 SYK (0.64) SYKCD63
SCHEMBL13337412 0.82 SYK (0.66) SYKCD63
SCHEMBL2479524 0.80 SYK (0.60) SYKCD63

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2010068257-A1 IMIDAZOPYRAZINE SYK INHIBITORS CGI PHARMACEUTICALS, INC. (US) 2010-06-17 WO disclosed