SCHEMBL13337828

SCHEMBL13337828

COc1cc(Nc2nc(-c3ccc4c(c3)OCCO4)cn3ccnc23)ccc1N1CCCCC1

nearest known ligand 0.65

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
SYK P43405 20/20 0.65
CD63 P08962 2/20 0.54

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL2481277 0.93 SYK (0.74) SYKCD63
SCHEMBL2481690 0.90 SYK (0.72) SYKCD63
SCHEMBL18455218 0.90 SYK (0.80) SYKCD63
SCHEMBL2481340 0.88 SYK (0.79) SYKCD63
SCHEMBL2481696 0.83 SYK (0.80) SYKCD63
SCHEMBL2481067 0.83 SYK (0.74) SYKCD63
SCHEMBL2898379 0.82 SYK (0.87) SYK
SCHEMBL15552706 0.82 SYK (0.69) SYKCD63
SCHEMBL2481004 0.81 SYK (0.80) SYKCD63
SCHEMBL2482310 0.81 SYK (0.66) SYKCD63

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2010068257-A1 IMIDAZOPYRAZINE SYK INHIBITORS CGI PHARMACEUTICALS, INC. (US) 2010-06-17 WO disclosed