⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13117368 | 0.88 | — | — | |
| SCHEMBL9420826 | 0.85 | — | — | |
| SCHEMBL14024405 | 0.80 | — | — | |
| SCHEMBL1127543 | 0.71 | — | — | |
| SCHEMBL936061 | 0.71 | — | — | |
| SCHEMBL23668 | 0.71 | — | — | |
| Hydrochloric Acid SCHEMBL29102309 | 0.68 | — | — | |
| SCHEMBL2286726 | 0.67 | — | — | |
| SCHEMBL12571326 | 0.67 | — | — | |
| SCHEMBL2261149 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7723509-B2 | Conjugated lipophilic group with a modified nucleotide is used to target disease gene, cells, tissue, for drug delivery to target tumor cells; ribose sugar of nucleotide is replaced with a cyclic carrier which has at least one attached phosphate or phosphorothioate group; biodrugs | ALNYLAM PHARMACEUTICALS (US) | 2010-05-25 | — | — | US | disclosed |