Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPK9 | P45984 | 17/20 | 0.73 |
| ▸ | CSNK1D | P48730 | 17/20 | 0.73 |
| ▸ | CSNK1A1 | P48729 | 14/20 | 0.73 |
| ▸ | MAP4K4 | O95819 | 14/20 | 0.73 |
| ▸ | PRKD2 | Q9BZL6 | 13/20 | 0.73 |
| ▸ | TAOK1 | Q7L7X3 | 11/20 | 0.73 |
| ▸ | MAPK8 | P45983 | 11/20 | 0.73 |
| ▸ | LIMK1 | P53667 | 8/20 | 0.73 |
| ▸ | MAPK1 | P28482 | 5/20 | 0.73 |
| ▸ | MAPK14 | Q16539 | 3/20 | 0.73 |
| ▸ | PRKD3 | O94806 | 14/20 | 0.72 |
| ▸ | CSNK1G2 | P78368 | 10/20 | 0.70 |
| ▸ | MINK1 | Q8N4C8 | 10/20 | 0.70 |
| ▸ | MAP4K5 | Q9Y4K4 | 9/20 | 0.70 |
| ▸ | CSNK1G3 | Q9Y6M4 | 9/20 | 0.70 |
| ▸ | CSNK1G1 | Q9HCP0 | 7/20 | 0.70 |
| ▸ | GSK3B | P49841 | 6/20 | 0.70 |
| ▸ | FGFR1 | P11362 | 4/20 | 0.70 |
| ▸ | PLK4 | O00444 | 1/20 | 0.70 |
| ▸ | KDR | P35968 | 2/20 | 0.69 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3520325 | 0.93 | MAPK9 (0.84) | MAPK9CSNK1DCSNK1A1MAP4K4PRKD2 | |
| SCHEMBL3523160 | 0.84 | MAPK9 (1.00) | MAPK9CSNK1DCSNK1A1MAP4K4PRKD2 | |
| SCHEMBL3523402 | 0.79 | MAPK9 (1.00) | MAPK9CSNK1DCSNK1A1MAP4K4PRKD2 | |
| SCHEMBL3526247 | 0.78 | CSNK1E (0.71) | MAPK9CSNK1DCSNK1A1MAP4K4PRKD2 | |
| SCHEMBL3523995 | 0.77 | MAPK9 (0.80) | MAPK9CSNK1DCSNK1A1MAP4K4PRKD2 | |
| SCHEMBL27741884 | 0.77 | MAPK9 (0.78) | MAPK9CSNK1DCSNK1A1MAP4K4PRKD2 | |
| SCHEMBL3525223 | 0.77 | GRIA1 (0.55) | MAPK9CSNK1DCSNK1A1MAP4K4PRKD2 | |
| SCHEMBL3529061 | 0.75 | MAPK9 (0.73) | MAPK9CSNK1DCSNK1A1MAP4K4PRKD2 | |
| SCHEMBL3523789 | 0.74 | MAPK9 (1.00) | MAPK9CSNK1DCSNK1A1MAP4K4PRKD2 | |
| SCHEMBL3528599 | 0.74 | MAPK9 (0.79) | MAPK9CSNK1DCSNK1A1MAP4K4PRKD2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7709468-B2 | Imidazo based heterocycles | ABBOTT LABORATORIES (US) | 2010-05-04 | — | — | US | disclosed |
| US-20070099925-A1 | Novel imidazo based heterocycles | ABBVIE INC. | 2007-05-03 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20070099925-A1 | Novel imidazo based heterocycles | CDK4, CDK2, MAP3K19 | MAPK9 189/4885CSNK1D 281/4885CSNK1A1 77/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.