Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | IL2RA | P01589 | 1/20 | 0.68 |
| ▸ | ALB | P02768 | 1/20 | 0.68 |
| ▸ | IL2 | P60568 | 1/20 | 0.68 |
| ▸ | MMP2 | P08253 | 2/20 | 0.51 |
| ▸ | MMP8 | P22894 | 2/20 | 0.51 |
| ▸ | MMP12 | P39900 | 2/20 | 0.51 |
| ▸ | MMP3 | P08254 | 1/20 | 0.51 |
| ▸ | MMP10 | P09238 | 1/20 | 0.51 |
| ▸ | MMP13 | P45452 | 1/20 | 0.51 |
| ▸ | F2 | P00734 | 13/20 | 0.47 |
| ▸ | F10 | P00742 | 1/20 | 0.46 |
| ▸ | ITGB1 | P05556 | 1/20 | 0.44 |
| ▸ | ITGA4 | P13612 | 1/20 | 0.44 |
| ▸ | EED | O75530 | 1/20 | 0.42 |
| ▸ | PRSS1 | P07477 | 2/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4993522 | 0.82 | IL2RA (0.84) | IL2RAALBIL2MMP2MMP8 | |
| SCHEMBL4323684 | 0.82 | IL2RA (0.84) | IL2RAALBIL2MMP2MMP8 | |
| SCHEMBL4323694 | 0.82 | IL2RA (0.84) | IL2RAALBIL2MMP2MMP8 | |
| SCHEMBL4323700 | 0.82 | IL2RA (0.84) | IL2RAALBIL2MMP2MMP8 | |
| SCHEMBL6860596 | 0.81 | IL2RA (1.00) | IL2RAALBIL2ITGB1ITGA4 | |
| SCHEMBL6860593 | 0.81 | IL2RA (1.00) | IL2RAALBIL2ITGB1ITGA4 | |
| SCHEMBL14136720 | 0.81 | IL2RA (1.00) | IL2RAALBIL2ITGB1ITGA4 | |
| SCHEMBL14136732 | 0.81 | IL2RA (1.00) | IL2RAALBIL2ITGB1ITGA4 | |
| SCHEMBL15159835 | 0.80 | IL2RA (0.77) | IL2RAALBIL2F2F10 | |
| SCHEMBL15159838 | 0.80 | IL2RA (0.85) | IL2RAALBIL2F2ITGB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010068923-A2 | AGENTS THAT SELECTIVELY INHIBIT CD25 ON DENDRITIC CELLS OR T CELLS AND THEIR USE | THE UNITED STATES OF AMERICA, AS REPRESENTED BY THE SECRETARY, DEPARTMENT OF HEALTH AND HUMAN SERVICES (US) | 2010-06-17 | — | — | WO | disclosed |