SCHEMBL133426

SCHEMBL133426

CC(C)=CCC[O]

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL7354471 0.84 KMT2A (0.73)
SCHEMBL7299167 0.84 KMT2A (0.73)
SCHEMBL10400158 0.81
SCHEMBL1276454 0.78 KMT2A (0.65)
SCHEMBL2162531 0.78
SCHEMBL127274 0.73
SCHEMBL6739869 0.73
SCHEMBL10400482 0.73
SCHEMBL10400483 0.73
SCHEMBL8078444 0.72 KMT2A (0.50)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 518 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-11993603-B2 Preparation for 6-amino-1H-pyrazolo[3,4-d]pyrimidine-based JAK kinase inhibitor and application thereof INSTITUTE OF MATERIA MEDICA, CHINESE ACADEMY OF MEDICAL SCIENCES & PEKING UNION MEDICAL COLLEGE (CN) 2024-05-28 US disclosed
CN-115551869-B Condensed ring 2-pyridone compounds, process for their preparation and their use in the treatment and/or prophylaxis of diseases involving gram-positive bacteria 快尔生物技术公司 2024-01-02 CN disclosed
EP-3828177-B1 PYRIDONE COMPOUND AND AGRICULTURAL AND HORTICULTURAL FUNGICIDE HAVING THIS AS ACTIVE COMPONENT MITSUI CHEMICALS CROP & LIFE SOLUTIONS INC (JP) 2023-11-29 EP disclosed
US-20230339973-A1 RING-FUSED 2-PYRIDONE COMPOUNDS, METHODS FOR PREPARATION THEREOF AND THEIR USE IN THE TREATMENT AND/OR PREVENTION OF A DISEASE INVOLVING GRAM-POSITIVE BACTERIA QURETECH BIO AB (SE) 2023-10-26 US disclosed
CN-110234627-B Pyridone compound and agricultural/horticultural bactericide containing pyridone compound as active ingredient 三井化学植保株式会社 2023-09-01 CN disclosed
EP-3611165-B1 PYRIDONE COMPOUND, AND AGRICULTURAL AND HORTICULTURAL FUNGICIDE HAVING THIS AS ACTIVE COMPONENT MITSUI CHEMICALS CROP & LIFE SOLUTIONS INC (JP) 2023-08-16 EP disclosed
EP-4219477-A1 CYANOTRIAZOLE COMPOUNDS Otsuka Pharmaceutical Co., Ltd. (JP) 2023-08-02 EP disclosed
US-20230233536-A1 RING-FUSED THIAZOLINO 2-PYRIDONES, METHODS FOR PREPARATION THEREOF AND THEIR USE IN THE TREATMENT AND/OR PREVENTION OF A DISEASE INVOLVING GRAM-POSITIVE BACTERIA QURETECH BIO AB (SE) 2023-07-27 US disclosed
CN-110799513-B Ring-fused thiazolo-2-pyridones, method for the production thereof and use thereof for treating and/or preventing diseases which involve gram-positive bacteria 快尔生物技术公司 2023-04-14 CN disclosed
EP-4146659-A1 RING-FUSED 2-PYRIDONE COMPOUNDS, METHODS FOR PREPARATION THEREOF AND THEIR USE IN THE TREATMENT AND/OR PREVENTION OF A DISEASE INVOLVING GRAM-POSITIVE BACTERIA Quretech Bio AB (SE) 2023-03-15 EP disclosed
EP-0456090-A2 Herbicidal agents containing cyclohexenone derivatives as active ingredients and naphthalene derivatives as antidotes BASF Aktiengesellschaft (DE) 1991-11-13 EP disclosed
US-5022914-A Pre- and post-emergence; broad leaf plants; rice BASF AKTIENGESELLSCHAFT (DE) 1991-06-11 US disclosed
EP-0414058-A2 Carboxylic acid derivatives BASF Aktiengesellschaft (DE) 1991-02-27 EP disclosed
EP-0414112-A2 Herbicides thiadiazabicyclononan derivatives BASF Aktiengesellschaft (DE) 1991-02-27 EP disclosed
EP-0398115-A1 Herbicidal n-phenyltetrahydrophthalimides, preparation and compositions BASF Aktiengesellschaft (DE) 1990-11-22 EP disclosed
EP-0368227-A1 Cyclohexenone oxime ethers, process for their preparation and their use as herbicides BASF Aktiengesellschaft (DE) 1990-05-16 EP disclosed
US-4914116-A Nitrogen-containing heterocyclic compounds, and their use as insecticides SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1990-04-03 US disclosed
US-4847259-A Nitrogen-containing heterocyclic compounds, and use as insecticide SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1989-07-11 US disclosed
US-4714706-A JUVENILE HORMONE INHIBITORS SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1987-12-22 US disclosed
EP-0203798-A2 Nitrogen-containing heterocyclic compounds, and their production and use SUMITOMO CHEMICAL COMPANY, LIMITED (JP) 1986-12-03 EP disclosed