⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13808963 | 1.00 | — | — | |
| SCHEMBL13749658 | 1.00 | — | — | |
| SCHEMBL10224591 | 1.00 | — | — | |
| SCHEMBL13344265 | 1.00 | — | — | |
| SCHEMBL13344273 | 1.00 | — | — | |
| SCHEMBL14346153 | 1.00 | — | — | |
| SCHEMBL13344269 | 1.00 | — | — | |
| SCHEMBL13344274 | 1.00 | — | — | |
| SCHEMBL12262873 | 1.00 | — | — | |
| SCHEMBL12162238 | 1.00 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8435762-B2 | Chimeric ligand-gated ion channels and methods of use thereof | HOWARD HUGHES MEDICAL INSTITUTE (US) | 2013-05-07 | — | — | US | disclosed |
| US-20100130420-A1 | NOVEL CHIMERIC LIGAND-GATED ION CHANNELS AND METHODS OF USE THEREOF | HOWARD HUGHES MEDICAL INSTITUTE (US) | 2010-05-27 | — | — | US | disclosed |