Chloromethane

Chloromethane

SCHEMBL1334447

C=CC(=O)NN(C)C.CCl

nearest known ligand 0.41

Full drug profile on Sugi Atlas →

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
TSHR P16473 2/20 0.41
LMNA P02545 2/20 0.40
ALDH1A1 P00352 3/20 0.39
MAPK1 P28482 1/20 0.39
TDP1 Q9NUW8 1/20 0.39
TGM2 P21980 4/20 0.33
KDM7A Q6ZMT4 1/20 0.33
PHF8 Q9UPP1 1/20 0.33
KDM2A Q9Y2K7 1/20 0.33
ZDHHC20 Q5W0Z9 1/20 0.33
ZDHHC2 Q9UIJ5 1/20 0.33
GSTO1 P78417 1/20 0.33
CYP3A4 P08684 1/20 0.32
CYP2C9 P11712 1/20 0.32
CYP2C19 P33261 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL471967 0.95
Hydrochloric Acid SCHEMBL28164352 0.92
Cyclopropane SCHEMBL21806779 0.88 TSHR (0.44) TSHRLMNAALDH1A1MAPK1TDP1
SCHEMBL29207900 0.77
SCHEMBL10819001 0.73 TSHR (0.39) TSHRLMNAALDH1A1MAPK1TDP1
SCHEMBL14876752 0.73
Trimethylammonium SCHEMBL28937285 0.72 TSHR (0.42) TSHRLMNAALDH1A1MAPK1TDP1
SCHEMBL28669538 0.71
SCHEMBL28053903 0.71
Chloromethane SCHEMBL27888220 0.70

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8753686-B2 Surface-treating agents, surface-treated powders, and cosmetics comprising the same SHISEIDO CO., LTD. (JP) 2014-06-17 US disclosed
US-20110280946-A1 Surface-Treating Agents, Surface-Treated Powders, And Cosmetics Comprising The Same SHISEIDO CO., LTD. (JP) 2011-11-17 US disclosed
EP-2112179-B1 Surface-treated powders, and cosmetics comprising the same SHISEIDO CO LTD (JP) 2011-04-27 EP disclosed
CN-100584865-C Surface treatment agent, surface-treated powder, and cosmetic containing the surface-treated powder SHISEIDO CO LTD 2010-01-27 CN disclosed
EP-1803750-B1 USE OF A POLYMER FOR SURFACE-TREATING A POWDER SHISEIDO CO LTD (JP) 2009-12-09 EP disclosed
EP-2112179-A1 Surface-treated powders, and cosmetics comprising the same Shiseido Co., Ltd. (JP) 2009-10-28 EP disclosed
US-20080081029-A1 acrylic homopolymers or copolymers, that can provide excellent hydrophobicity to powders or cosmetics, and can improve its rinsability SHISEIDO CO., LTD. (JP) 2008-04-03 US disclosed
CN-101035819-A Surface treatment agent, surface-treated powder, and cosmetic containing the surface-treated powder SHISEIDO CO LTD (JP) 2007-09-12 CN disclosed
EP-1803750-A1 SURFACE-TREATING AGENT, SURFACE-TREATED POWDER, AND COSMETIC PREPARATION CONTAINING SAME Shiseido Company, Limited (JP) 2007-07-04 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080081029-A1 acrylic homopolymers or copolymers, that can provide excellent hydrophobicity to powders or cosmetics, and can improve its rinsability CHRM1, H1-0, H1-2 TSHR 1868/4885LMNA 2921/4885ALDH1A1 142/4885
US-20110280946-A1 Surface-Treating Agents, Surface-Treated Powders, And Cosmetics Comprising The Same CHRM1, H1-0, H1-2 TSHR 655/4885LMNA 1417/4885ALDH1A1 115/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.