Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CXCR2 | P25025 | 18/20 | 0.63 |
| ▸ | CXCR1 | P25024 | 13/20 | 0.63 |
| ▸ | CCR7 | P32248 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13208185 | 0.89 | CXCR1 (0.80) | CXCR2CXCR1 | |
| SCHEMBL13344788 | 0.89 | CXCR1 (0.80) | CXCR2CXCR1CCR7 | |
| SCHEMBL13207182 | 0.88 | CXCR2 (0.62) | CXCR2CXCR1CCR7 | |
| SCHEMBL12262389 | 0.86 | CXCR2 (0.78) | CXCR2CXCR1CCR7 | |
| SCHEMBL13407515 | 0.84 | CXCR2 (0.62) | CXCR2CXCR1CCR7 | |
| SCHEMBL13345403 | 0.80 | CXCR2 (0.73) | CXCR2CXCR1CCR7 | |
| SCHEMBL13344785 | 0.79 | CXCR2 (0.61) | CXCR2CXCR1CCR7 | |
| SCHEMBL13344764 | 0.79 | CXCR1 (0.79) | CXCR2CXCR1CCR7 | |
| SCHEMBL13208144 | 0.78 | CXCR1 (1.00) | CXCR2CXCR1 | |
| SCHEMBL13345408 | 0.78 | CXCR2 (0.78) | CXCR2CXCR1CCR7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7718678-B2 | Di-substituted oxadiazoles as CXC-chemokine receptor ligands | SCHERING CORPORATION (US) | 2010-05-18 | — | — | US | disclosed |
| US-7718678-B2 | Di-substituted oxadiazoles as CXC-chemokine receptor ligands | SCHERING CORPORATION (US) | 2010-05-18 | — | — | US | disclosed |