SCHEMBL1334575

SCHEMBL1334575

NC(N)(F)F

nearest known ligand 0.00

⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Lithium SCHEMBL31206119 0.93
SCHEMBL23617 0.83
SCHEMBL31532230 0.83
Hydrochloric Acid SCHEMBL9376252 0.77
SCHEMBL5513240 0.77
Bromide SCHEMBL5108256 0.77
Water SCHEMBL18979260 0.77
Lithium Ion SCHEMBL31206225 0.74
SCHEMBL15280130 0.72
SCHEMBL13837950 0.72

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 33 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-8203003-B2 4-fluoropyrrolidine-2-carbonyl fluoride compounds and their preparative methods UBE INDUSTRIES, LTD. (JP) 2012-06-19 US claimed
US-20110275833-A1 Novel 4-Fluoropyrrolidine-2-Carbonyl Fluoride Compounds and Their Preparative Methods UBE INDUSTRIES, LTD. (JP) 2011-11-10 US claimed
WO-2010081014-A1 NOVEL 4-FLUOROPYRROLIDINE-2-CARBONYL FLUORIDE COMPOUNDS AND THEIR PREPARATIVE METHODS IM&T RESEARCH, INC. (US) 2010-07-15 WO claimed
EP-0203466-B1 PROCESS FOR THE PREPARATION OF 2-PERFLUOROPROPOXY-PERFLUOROPROPIONYL FLUORIDE AUSIMONT S.r.l. (IT) 1990-11-28 EP claimed
US-4729856-A DIMERIZATION AUSIMONT S.P.A. (IT) 1988-03-08 US claimed
EP-0203466-A2 Process for the preparation of 2-perfluoropropoxy-perfluoropropionyl fluoride AUSIMONT S.r.l. (IT) 1986-12-03 EP claimed
US-4118421-A Process for the manufacture of perfluoro-alkoxy-propionic acid fluorides HOECHST AKTIENGESELLSCHAFT (DE) 1978-10-03 US claimed
US-12043606-B2 Fluorolactone and method for producing same DAIKIN INDUSTRIES, LTD. (JP) 2024-07-23 US disclosed
US-20220064139-A1 FLUOROLACTONE AND METHOD FOR PRODUCING SAME DAIKIN INDUSTRIES, LTD. (JP) 2022-03-03 US disclosed
WO-2020230822-A1 FLUOROLACTONE AND METHOD FOR PRODUCING SAME ダイキン工業株式会社 2020-11-19 WO disclosed
CN-103664973-B Spiro-oxindole compounds and their use as therapeutic agents 泽农医药公司 2017-04-19 CN disclosed
WO-2016124564-A1 N-SUBSTITUTED 8-[(2,6-DIFLUOROBENZYL)OXY]-2,6-DIMETHYLIMIDAZO[1,2-A]PYRAZIN-3-CARBOXAMIDE DERIVATIVES AS STIMULATORS OF SOLUBLE GUANYLATE CYLASE (SGC) FOR THE TREATMENT OF CARDIOVASCULAR DISEASES BAYER PHARMA AKTIENGESELLSCHAFT (DE) 2016-08-11 WO disclosed
WO-2016124565-A1 SUBSTITUTED PYRAZOLO[1,5-A]-PYRIDINE-3-CARBOXAMIDES AND USE THEREOF BAYER PHARMA AKTIENGESELLSCHAFT (DE) 2016-08-11 WO disclosed
US-4749526-A Process for preparing fluoraliphatic ether-containing carbonyl fluoride compositions MINNESOTA MINING AND MANUFACTURING CO. (US) 1988-06-07 US disclosed
EP-0265052-A1 Process for preparing fluoroaliphatic ether-containing carbonyl fluoride compositions MINNESOTA MINING AND MANUFACTURING COMPANY (US) 1988-04-27 EP disclosed
US-4729856-A DIMERIZATION AUSIMONT S.P.A. (IT) 1988-03-08 US disclosed
US-4729856-A DIMERIZATION AUSIMONT S.P.A. (IT) 1988-03-08 US disclosed
EP-0203466-A2 Process for the preparation of 2-perfluoropropoxy-perfluoropropionyl fluoride AUSIMONT S.r.l. (IT) 1986-12-03 EP disclosed
EP-0203466-A2 Process for the preparation of 2-perfluoropropoxy-perfluoropropionyl fluoride AUSIMONT S.r.l. (IT) 1986-12-03 EP disclosed
US-4118421-A Process for the manufacture of perfluoro-alkoxy-propionic acid fluorides HOECHST AKTIENGESELLSCHAFT (DE) 1978-10-03 US disclosed