Predicted protein targets (top 1)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ATR | Q13535 | 20/20 | 0.82 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13138056 | 0.90 | ATR (0.85) | ATR | |
| SCHEMBL13138239 | 0.90 | ATR (1.00) | ATR | |
| SCHEMBL3052735 | 0.90 | ATR (0.84) | ATR | |
| SCHEMBL13138008 | 0.90 | ATR (1.00) | ATR | |
| SCHEMBL2511649 | 0.89 | ATR (1.00) | ATR | |
| SCHEMBL2511882 | 0.87 | ATR (0.86) | ATR | |
| SCHEMBL13138183 | 0.87 | ATR (1.00) | ATR | |
| SCHEMBL2481966 | 0.87 | ATR (1.00) | ATR | |
| SCHEMBL13138259 | 0.86 | ATR (1.00) | ATR | |
| SCHEMBL2487653 | 0.86 | ATR (0.78) | ATR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010071837-A1 | PYRAZINE DERIVATIVES USEFUL AS INHIBITORS OF ATR KINASE | VERTEX PHARMACEUTICALS INCORPORATED (US) | 2010-06-24 | — | — | WO | disclosed |