Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 11/20 | 1.00 |
| ▸ | HSD17B10 | Q99714 | 7/20 | 1.00 |
| ▸ | HPGD | P15428 | 6/20 | 1.00 |
| ▸ | MAPT | P10636 | 1/20 | 1.00 |
| ▸ | ALDH1A1 | P00352 | 10/20 | 0.63 |
| ▸ | ESR1 | P03372 | 2/20 | 0.63 |
| ▸ | HMGB1 | P09429 | 2/20 | 0.63 |
| ▸ | NAPRT | Q6XQN6 | 2/20 | 0.63 |
| ▸ | ITGB3 | P05106 | 1/20 | 0.63 |
| ▸ | ITGA2B | P08514 | 1/20 | 0.63 |
| ▸ | TSHR | P16473 | 1/20 | 0.63 |
| ▸ | GGT1 | P19440 | 1/20 | 0.63 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.63 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.63 |
| ▸ | BLM | P54132 | 1/20 | 0.63 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.63 |
| ▸ | LMNA | P02545 | 1/20 | 0.56 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.56 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.56 |
| ▸ | USP2 | O75604 | 1/20 | 0.52 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27652522 | 0.93 | KDM4E (0.86) | KDM4EHSD17B10HPGDMAPTALDH1A1 | |
| SCHEMBL21710510 | 0.91 | KDM4E (0.83) | KDM4EHSD17B10HPGDMAPTALDH1A1 | |
| Hydrochloric Acid SCHEMBL27652371 | 0.91 | KDM4E (0.83) | KDM4EHSD17B10HPGDMAPTALDH1A1 | |
| SCHEMBL12219587 | 0.91 | KDM4E (0.83) | KDM4EHSD17B10HPGDMAPTALDH1A1 | |
| SCHEMBL9320970 | 0.90 | KDM4E (0.81) | KDM4EHSD17B10HPGDMAPTALDH1A1 | |
| SCHEMBL7712909 | 0.89 | KDM4E (0.80) | KDM4EHSD17B10HPGDMAPTALDH1A1 | |
| SCHEMBL7712911 | 0.89 | KDM4E (0.80) | KDM4EHSD17B10HPGDMAPTALDH1A1 | |
| SCHEMBL21710416 | 0.87 | KDM4E (0.76) | KDM4EHSD17B10HPGDMAPTALDH1A1 | |
| SCHEMBL21710501 | 0.87 | KDM4E (0.76) | KDM4EHSD17B10HPGDMAPTALDH1A1 | |
| SCHEMBL8647754 | 0.86 | KDM4E (0.76) | KDM4EHSD17B10HPGDMAPTALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9200046-B2 | Reporter system for high throughput screening of compounds and uses thereof | CORNELL UNIVERSITY (US) | 2015-12-01 | — | — | US | disclosed |
| WO-2010056345-A2 | BIOFILM-INHIBITORY COATINGS THAT RELEASE SALICYCLIC ACID BY HYDROLISIS | BAYER MATERIALSCIENCE LLC (US) | 2010-05-20 | — | — | WO | disclosed |