Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SPHK1 | Q9NYA1 | 2/20 | 0.42 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.34 |
| ▸ | PLA2G1B | P04054 | 1/20 | 0.34 |
| ▸ | PLA2G2A | P14555 | 1/20 | 0.34 |
| ▸ | GMNN | O75496 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | THPO | P40225 | 1/20 | 0.34 |
| ▸ | MTOR | P42345 | 1/20 | 0.34 |
| ▸ | BLM | P54132 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.34 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | CETP | P11597 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | UBE2N | P61088 | 1/20 | 0.34 |
| ▸ | GNAI3 | P08754 | 1/20 | 0.34 |
| ▸ | GNAO1 | P09471 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13354519 | 1.00 | SPHK1 (0.42) | SPHK1CYP2D6PLA2G1BPLA2G2AGMNN | |
| SCHEMBL12977331 | 0.95 | SPHK1 (0.39) | SPHK1CYP2D6PLA2G1BPLA2G2AGMNN | |
| SCHEMBL12977340 | 0.94 | SPHK1 (0.38) | SPHK1CYP2D6PLA2G1BPLA2G2AGMNN | |
| SCHEMBL16500375 | 0.91 | SPHK1 (0.38) | SPHK1CYP2D6PLA2G1BPLA2G2AGMNN | |
| SCHEMBL13354385 | 0.88 | SPHK1 (0.41) | SPHK1CYP2D6PLA2G1BPLA2G2AGMNN | |
| SCHEMBL12977339 | 0.86 | SPHK1 (0.36) | SPHK1CYP2D6PLA2G1BPLA2G2AGMNN | |
| SCHEMBL13354383 | 0.84 | SPHK1 (0.49) | SPHK1CYP2D6GMNNLMNAPOLB | |
| SCHEMBL16919611 | 0.84 | SPHK1 (0.34) | SPHK1ADRB2ADRB1 | |
| SCHEMBL12977338 | 0.83 | SPHK1 (0.33) | SPHK1 | |
| SCHEMBL12977356 | 0.81 | SPHK1 (0.32) | SPHK1PLA2G1BPLA2G2AADRB2ADRB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010053572-A2 | AMINOALCOHOL LIPIDOIDS AND USES THEREOF | MASSACHUSETTS INSTITUTE OF TECHNOLOGY (US) | 2010-05-14 | — | — | WO | disclosed |