Predicted protein targets (top 7)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDPK1 | O15530 | 19/20 | 0.84 |
| ▸ | AURKB | Q96GD4 | 15/20 | 0.84 |
| ▸ | AURKA | O14965 | 11/20 | 0.84 |
| ▸ | ROCK1 | Q13464 | 10/20 | 0.84 |
| ▸ | TGFBR1 | P36897 | 1/20 | 0.64 |
| ▸ | GSK3A | P49840 | 1/20 | 0.46 |
| ▸ | GSK3B | P49841 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL1317520 | 0.91 | PDPK1 (1.00) | PDPK1AURKBAURKAROCK1TGFBR1 | |
| SCHEMBL1319787 | 0.91 | PDPK1 (1.00) | PDPK1AURKBAURKAROCK1TGFBR1 | |
| SCHEMBL1319260 | 0.86 | PDPK1 (0.91) | PDPK1AURKBAURKAROCK1TGFBR1 | |
| SCHEMBL1319538 | 0.85 | PDPK1 (0.85) | PDPK1AURKBAURKAROCK1TGFBR1 | |
| SCHEMBL16966498 | 0.85 | PDPK1 (0.84) | PDPK1AURKBAURKAROCK1TGFBR1 | |
| SCHEMBL1318359 | 0.85 | PDPK1 (0.84) | PDPK1AURKBAURKAROCK1TGFBR1 | |
| SCHEMBL1319921 | 0.84 | PDPK1 (0.85) | PDPK1AURKBAURKAROCK1TGFBR1 | |
| SCHEMBL1319259 | 0.84 | PDPK1 (0.85) | PDPK1AURKBAURKAROCK1TGFBR1 | |
| SCHEMBL1317749 | 0.83 | PDPK1 (0.81) | PDPK1AURKBAURKAROCK1TGFBR1 | |
| SCHEMBL1319810 | 0.83 | PDPK1 (0.84) | PDPK1AURKBAURKAROCK1TGFBR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010059658-A1 | CHEMICAL COMPOUNDS | GLAXOSMITHKLINE LLC (US) | 2010-05-27 | — | — | WO | disclosed |