Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LPAR3 | Q9UBY5 | 15/20 | 0.71 |
| ▸ | LPAR2 | Q9HBW0 | 12/20 | 0.71 |
| ▸ | LPAR1 | Q92633 | 8/20 | 0.71 |
| ▸ | P2RY10 | O00398 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13355654 | 1.00 | LPAR3 (0.71) | LPAR3LPAR2LPAR1P2RY10 | |
| SCHEMBL13355655 | 0.97 | LPAR3 (0.71) | LPAR3LPAR2LPAR1P2RY10 | |
| SCHEMBL8468251 | 0.90 | LPAR3 (0.80) | LPAR3LPAR2LPAR1 | |
| Dectaflur SCHEMBL11087909 | 0.86 | LPAR3 (0.69) | LPAR3LPAR2LPAR1P2RY10 | |
| SCHEMBL192973 | 0.83 | LPAR3 (1.00) | LPAR3LPAR2LPAR1 | |
| SCHEMBL10017367 | 0.83 | LPAR3 (1.00) | LPAR3LPAR2LPAR1 | |
| SCHEMBL10017369 | 0.83 | LPAR3 (1.00) | LPAR3LPAR2LPAR1 | |
| SCHEMBL3832990 | 0.83 | LPAR3 (1.00) | LPAR3LPAR2LPAR1 | |
| SCHEMBL18499859 | 0.83 | LPAR3 (0.69) | LPAR3LPAR2LPAR1 | |
| Dectaflur SCHEMBL11077288 | 0.83 | LPAR3 (0.64) | LPAR3LPAR2LPAR1P2RY10 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2262371-B1 | LPA RECEPTOR AGONISTS AND ANTAGONISTS | RXBIO INC (US) | 2014-01-01 | — | — | EP | disclosed |
| WO-2010051053-A1 | LPA RECEPTOR AGONISTS AND ANTAGONISTS | RXBIO, INC. (US) | 2010-05-06 | — | — | WO | disclosed |