Predicted protein targets (top 3)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARD | Q03181 | 19/20 | 0.48 |
| ▸ | PPARA | Q07869 | 10/20 | 0.44 |
| ▸ | PPARG | P37231 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12849456 | 0.89 | PPARD (0.48) | PPARDPPARAPPARG | |
| SCHEMBL13355777 | 0.81 | PPARD (0.62) | PPARDPPARA | |
| SCHEMBL13355773 | 0.79 | PPARD (0.50) | PPARDPPARA | |
| SCHEMBL3026881 | 0.79 | PPARD (0.62) | PPARDPPARA | |
| SCHEMBL1400983 | 0.76 | PPARA (0.70) | PPARDPPARAPPARG | |
| SCHEMBL13355774 | 0.76 | PPARA (0.48) | PPARDPPARAPPARG | |
| SCHEMBL12798942 | 0.76 | PPARD (0.52) | PPARDPPARA | |
| SCHEMBL1400882 | 0.75 | PPARA (0.71) | PPARDPPARAPPARG | |
| SCHEMBL1400860 | 0.75 | PPARA (0.72) | PPARDPPARAPPARG | |
| SCHEMBL1400945 | 0.75 | PPARA (0.71) | PPARDPPARAPPARG |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7714004-B2 | Indane acetic acid derivatives and their use as pharmaceutical agents, intermediates, and method of preparation | BAYER PHARMACEUTICALS CORPORATION (US) | 2010-05-11 | — | — | US | disclosed |