Known targets — ChEMBL curated mechanism
The experimentally established mechanism targets of None. The predicted profile below is derived independently by chemical similarity — agreement is a validation signal, a miss is honest.
Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CA4 | P22748 | 4/20 | 0.42 |
| ▸ | CTSL | P07711 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.37 |
| ▸ | FOLH1 | Q04609 | 2/20 | 0.34 |
| ▸ | EPHX2 | P34913 | 1/20 | 0.33 |
| ▸ | SLC22A16 | Q86VW1 | 1/20 | 0.32 |
| ▸ | CRAT | P43155 | 1/20 | 0.31 |
| ▸ | CPT2 | P23786 | 1/20 | 0.30 |
| ▸ | CPT1A | P50416 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6236316 | 0.95 | CA4 (0.42) | CA4CTSLCA2FOLH1EPHX2 | |
| SCHEMBL7789641 | 0.95 | CA4 (0.46) | CA4CTSLCA2FOLH1EPHX2 | |
| Potassium Ion SCHEMBL8761405 | 0.95 | CA4 (0.42) | CA4CTSLCA2FOLH1EPHX2 | |
| SCHEMBL2911531 | 0.95 | CA4 (0.46) | CA4CTSLCA2FOLH1EPHX2 | |
| SCHEMBL5688858 | 0.95 | CA4 (0.42) | CA4CTSLCA2FOLH1EPHX2 | |
| SCHEMBL6925266 | 0.95 | CA4 (0.42) | CA4CTSLCA2FOLH1EPHX2 | |
| SCHEMBL9119304 | 0.95 | CA4 (0.42) | CA4CTSLCA2FOLH1EPHX2 | |
| SCHEMBL2916274 | 0.93 | CA4 (0.44) | CA4CTSLCA2FOLH1EPHX2 | |
| SCHEMBL30338181 | 0.93 | CA4 (0.44) | CA4CTSLCA2FOLH1EPHX2 | |
| SCHEMBL29354905 | 0.93 | CA4 (0.44) | CA4CTSLCA2FOLH1EPHX2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1945191-B1 | METAL COORDINATED COMPOSITIONS | SYNTHONICS INC (US) | 2017-11-08 | — | — | EP | disclosed |
| US-20150080433-A1 | METAL COORDINATED COMPOSITIONS | SYNTHONICS, INC. | 2015-03-19 | — | — | US | disclosed |
| US-20130184447-A1 | METAL COORDINATED COMPOSITIONS | SYNTHONICS, INC. (US) | 2013-07-18 | — | — | US | disclosed |
| US-8389726-B2 | Metal coordinated compositions | SYNTHONICS, INC. (US) | 2013-03-05 | — | — | US | disclosed |
| US-20110275792-A1 | METAL COORDINATED COMPOSITIONS | SYNTHONICS, INC. | 2011-11-10 | — | — | US | disclosed |
| US-7989440-B2 | Metal coordinated compositions | SYNTHONICS, INC. (US) | 2011-08-02 | — | — | US | disclosed |
| US-7799937-B2 | Metal coordinated compositions | SYNTHONICS, INC. (US) | 2010-09-21 | — | — | US | disclosed |
| US-20090143338-A1 | Metal coordinated compositions | PICCARIELLO THOMAS | 2009-06-04 | — | — | US | disclosed |
| EP-1945191-A2 | METAL COORDINATED COMPOSITIONS | Synthonics, Inc. (US) | 2008-07-23 | — | — | EP | disclosed |
| US-20080015352-A1 | Metal coordinated compositions | HTERT3, INC. | 2008-01-17 | — | — | US | disclosed |
| WO-2007050181-A2 | METAL COORDINATED COMPOSITIONS | SYNTHONICS, INC. (US) | 2007-05-03 | — | — | WO | disclosed |
| US-20060141054-A1 | Metal coordinated compositions | SYNTHONICS, INC. | 2006-06-29 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20080015352-A1 | Metal coordinated compositions | SLC30A6, SLC39A7, SLC39A14 | CA4 253/4885CTSL 1225/4885CA2 177/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.