⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL25200418 | 0.72 | — | — | |
| SCHEMBL1190048 | 0.70 | — | — | |
| SCHEMBL22731251 | 0.68 | — | — | |
| Ethyl Chloride SCHEMBL1052272 | 0.67 | FFAR3 (0.44) | — | |
| SCHEMBL8532418 | 0.67 | — | — | |
| SCHEMBL2672587 | 0.67 | — | — | |
| SCHEMBL28290466 | 0.67 | — | — | |
| SCHEMBL2671479 | 0.67 | — | — | |
| SCHEMBL92092 | 0.67 | — | — | |
| SCHEMBL298779 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 54 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-119118940-A | Preparation method of 2-chloromethyl-oxazole | 湖南唯美胜科技有限公司 | 2024-12-13 | — | — | CN | claimed |
| EP-1436286-B1 | FUMAGILLOL DERIVATIVES AND PREPARING METHOD THEREOF | EQUISPHARM CO LTD (KR) | 2009-08-19 | — | — | EP | claimed |
| US-7087768-B2 | 6-O-(4-methoxyaniline)acetyl fumagillol for example; superior angiogenesis inhibitory effect with less toxicity, also a cancer metastasis inhibitor, and treats angiogenesis related disorders such as other various inflammatory diseases such as rheumatic disease, psoriasis, and diabetic retinopathy | EQUISPHARM CO., LTD. (KR) | 2006-08-08 | — | — | US | claimed |
| EP-1436286-A4 | FUMAGILLOL DERIVATIVES AND PREPARING METHOD THEREOF | IDRTECH INC (KR) | 2004-12-15 | — | — | EP | claimed |
| US-20040242681-A1 | Fumagillol derivatives and preparing method thereof | EQUISPHARM CO., LTD. (KR) | 2004-12-02 | — | — | US | claimed |
| EP-1436286-A1 | FUMAGILLOL DERIVATIVES AND PREPARING METHOD THEREOF | Idrtech Inc. (KR) | 2004-07-14 | — | — | EP | claimed |
| WO-2003027104-A1 | FUMAGILLOL DERIVATIVES AND PREPARING METHOD THEREOF | IDRTECH INC. (KR) | 2003-04-03 | — | — | WO | claimed |
| US-12605451-B2 | Targeted plasma protein degradation | NOVARTIS AG (CH) | 2026-04-21 | — | — | US | disclosed |
| US-12209144-B2 | Cyclic peptides as proprotein convertase subtilisin/kexin type 9 (PCSK9) inhibitors for the treatment of metabolic disorders | NOVARTIS AG (CH) | 2025-01-28 | — | — | US | disclosed |
| CN-119118940-A | Preparation method of 2-chloromethyl-oxazole | 湖南唯美胜科技有限公司 | 2024-12-13 | — | — | CN | disclosed |
| CN-118434793-A | Main chain polymer, optical film, method for producing same, and multilayer film | 东曹株式会社 | 2024-08-02 | — | — | CN | disclosed |
| US-20230398224-A1 | TARGETED PLASMA PROTEIN DEGRADATION | NOVARTIS AG (CH) | 2023-12-14 | — | — | US | disclosed |
| EP-4100064-A1 | TARGETED PLASMA PROTEIN DEGRADATION | Novartis AG (CH) | 2022-12-14 | — | — | EP | disclosed |
| WO-2003027104-A1 | FUMAGILLOL DERIVATIVES AND PREPARING METHOD THEREOF | IDRTECH INC. (KR) | 2003-04-03 | — | — | WO | disclosed |
| US-6331653-B1 | Process for producing 3,4-dihydroxy-3-cyclobutene-1,2-dione | KYOWA YUKA CO., LTD. (JP) | 2001-12-18 | — | — | US | disclosed |
| CN-1269778-A | Preparation method of 3, 4-dihydroxy-3-cyclobutene-1, 2-diketone | KYOWA YUKA KK (JP) | 2000-10-11 | — | — | CN | disclosed |
| EP-1010684-A1 | PROCESS FOR PRODUCING 3,4-DIHYDROXY-3-CYCLOBUTENE-1,2-DIONE | Kyowa Yuka Co., Ltd. (JP) | 2000-06-21 | — | — | EP | disclosed |
| CN-1121064-A | Process for preparing trifluoroacetyl fluoride | HOECHST AG (DE) | 1996-04-24 | — | — | CN | disclosed |
| US-4235815-A | N-fluoromethyl-carbamic acid fluorides and their manufacture | BASF AKTIENGESELLSCHAFT (DE) | 1980-11-25 | — | — | US | disclosed |
| US-4179465-A | N-fluoromethyl-carbamic acid fluorides and their manufacture | BASF AKTIENGESELLSCHAFT (DE) | 1979-12-18 | — | — | US | disclosed |