SCHEMBL13358136

SCHEMBL13358136

NC[C@H]1CN(c2ccc(N3CCON(C(=O)c4cc5ccccc5o4)CC3)c(F)c2)C(=O)O1

nearest known ligand 0.52

Predicted protein targets (top 7)

geneUniProtsupporting neighboursconfidence
MAOB P27338 13/20 0.52
MAOA P21397 5/20 0.52
LMNA P02545 1/20 0.52
PTGS1 P23219 1/20 0.52
CALML3 P27482 1/20 0.52
SDHA P31040 1/20 0.52
F10 P00742 7/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10152203 0.90 MAOB (0.68) MAOBMAOALMNAPTGS1CALML3
SCHEMBL13367867 0.85 MAOB (0.57) MAOBMAOALMNAPTGS1CALML3
SCHEMBL13367952 0.84 MAOB (0.55) MAOBMAOALMNAPTGS1CALML3
SCHEMBL13368058 0.83 MAOB (0.49) MAOBMAOALMNAPTGS1CALML3
SCHEMBL13981052 0.83 MAOB (0.57) MAOBMAOALMNAPTGS1CALML3
SCHEMBL13357824 0.83 MAOB (0.54) MAOBMAOALMNAPTGS1CALML3
SCHEMBL13357818 0.83 MAOB (0.65) MAOBMAOALMNAPTGS1CALML3
SCHEMBL13368046 0.82 MAOB (0.52) MAOBMAOALMNAPTGS1CALML3
SCHEMBL13358149 0.82 MAOB (0.58) MAOBMAOALMNAPTGS1CALML3
SCHEMBL13357965 0.82 MAOB (0.58) MAOBMAOALMNAPTGS1CALML3

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-2181994-A1 Antimicrobial compounds Research Foundation Itsuu Laboratory (JP) 2010-05-05 EP disclosed
EP-2181993-A1 Antimicrobial oxazolidinone derivatives Research Foundation Itsuu Laboratory (JP) 2010-05-05 EP disclosed
EP-2009012-A1 NOVEL COMPOUND HAVING HETEROCYCLIC RING Research Foundation Itsuu Laboratory (JP) 2008-12-31 EP disclosed