Uracil

Uracil

SCHEMBL1335832

O=c1cc[nH]c(=O)[nH]1.OCCC1(O)OCCC1O

nearest known ligand 0.42

Full drug profile on Sugi Atlas →

Predicted protein targets (top 1)

geneUniProtsupporting neighboursconfidence
CRBN Q96SW2 1/20 0.42

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Uracil SCHEMBL48372 0.71 CRBN (0.77) CRBN
Uracil SCHEMBL7108401 0.68 CRBN (0.44) CRBN
Uracil SCHEMBL29217819 0.67 CRBN (0.94) CRBN
Uracil SCHEMBL27589685 0.67
Uracil SCHEMBL31242545 0.67 CRBN (0.94) CRBN
Uracil SCHEMBL11607890 0.65
Uracil SCHEMBL8235 0.65
Uracil SCHEMBL2825258 0.64 CRBN (0.63) CRBN
Uracil SCHEMBL28426792 0.64 CRBN (0.85) CRBN
Uracil SCHEMBL156275 0.63

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20110280931-A1 MATRIX METALLOPROTEINASE INHIBITOR GROB CURT HAROLD (US) 2011-11-17 US disclosed