Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ABCG2 | Q9UNQ0 | 2/20 | 0.49 |
| ▸ | PPARA | Q07869 | 3/20 | 0.48 |
| ▸ | PPARG | P37231 | 3/20 | 0.48 |
| ▸ | PPARD | Q03181 | 2/20 | 0.48 |
| ▸ | BCHE | P06276 | 11/20 | 0.48 |
| ▸ | ACHE | P22303 | 9/20 | 0.48 |
| ▸ | EGFR | P00533 | 1/20 | 0.44 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.44 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.44 |
| ▸ | HDAC6 | Q9UBN7 | 1/20 | 0.44 |
| ▸ | CYP1A1 | P04798 | 1/20 | 0.44 |
| ▸ | CYP1B1 | Q16678 | 1/20 | 0.44 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13764708 | 0.91 | ABCG2 (0.51) | ABCG2PPARAPPARGPPARDBCHE | |
| SCHEMBL815541 | 0.91 | ABCG2 (0.51) | ABCG2PPARAPPARGPPARDBCHE | |
| SCHEMBL814668 | 0.88 | PPARA (0.63) | ABCG2PPARAPPARGPPARDBCHE | |
| SCHEMBL13764711 | 0.88 | PPARA (0.63) | ABCG2PPARAPPARGPPARDBCHE | |
| SCHEMBL13769128 | 0.85 | ABCG2 (0.49) | ABCG2PPARABCHEACHEEGFR | |
| SCHEMBL13764714 | 0.84 | ABCG2 (0.54) | ABCG2PPARAPPARGPPARDBCHE | |
| SCHEMBL11893163 | 0.82 | PPARA (0.48) | ABCG2PPARAPPARGPPARDBCHE | |
| SCHEMBL1934560 | 0.82 | PPARA (0.48) | ABCG2PPARAPPARGPPARDBCHE | |
| SCHEMBL11893218 | 0.81 | PPARA (0.67) | ABCG2PPARAPPARGPPARDBCHE | |
| SCHEMBL11893235 | 0.80 | PPARA (0.45) | ABCG2PPARAPPARGPPARD |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1644312-B1 | PREPARATION OF 1,3-DIPHENYLPROP-2-EN-1-ONE DERIVATIVES | GENFIT (FR) | 2010-05-19 | — | — | EP | disclosed |