⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7877829 | 0.75 | — | — | |
| SCHEMBL140582 | 0.75 | — | — | |
| Dimethyl Succinate SCHEMBL31517013 | 0.75 | TSHR (0.56) | — | |
| Hydrochloric Acid SCHEMBL28882431 | 0.73 | — | — | |
| Water SCHEMBL29287946 | 0.73 | — | — | |
| SCHEMBL2600114 | 0.73 | — | — | |
| SCHEMBL13430572 | 0.73 | — | — | |
| SCHEMBL23270889 | 0.72 | — | — | |
| SCHEMBL12396689 | 0.71 | — | — | |
| SCHEMBL18863908 | 0.71 | TSHR (0.50) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2190841-B1 | SUBSTITUTED OXAZOLIDINONE DERIVATIVES | CONCERT PHARMACEUTICALS INC (US) | 2013-05-15 | — | — | EP | disclosed |
| US-8227464-B2 | Substituted oxazolidinone derivatives | CONCERT PHARMACEUTICALS, INC. (US) | 2012-07-24 | — | — | US | disclosed |
| US-20110281828-A1 | SUBSTITUTED OXAZOLIDINONE DERIVATIVES | CONCERT PHARMACEUTICALS INC. | 2011-11-17 | — | — | US | disclosed |
| US-7985750-B2 | Substituted oxazolidinone derivatives | CONCERT PHARMACEUTICALS, INC. (US) | 2011-07-26 | — | — | US | disclosed |
| US-7985750-B2 | Substituted oxazolidinone derivatives | CONCERT PHARMACEUTICALS, INC. (US) | 2011-07-26 | — | — | US | disclosed |
| EP-2190841-A1 | SUBSTITUTED OXAZOLIDINONE DERIVATIVES | Concert Pharmaceuticals Inc. (US) | 2010-06-02 | — | — | EP | disclosed |
| US-20090137535-A1 | Substituted oxazolidinone derivatives | SUN PHARMACEUTICAL INDUSTRIES, INC. | 2009-05-28 | — | — | US | disclosed |
| US-20090137535-A1 | Substituted oxazolidinone derivatives | SUN PHARMACEUTICAL INDUSTRIES, INC. | 2009-05-28 | — | — | US | disclosed |
| WO-2009023233-A1 | SUBSTITUTED OXAZOLIDINONE DERIVATIVES | CONCERT PHARMACEUTICALS, INC. (US) | 2009-02-19 | — | — | WO | disclosed |