Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.38 |
| ▸ | MEN1 | O00255 | 2/20 | 0.38 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.38 |
| ▸ | CTSK | P43235 | 3/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.33 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.32 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.32 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.32 |
| ▸ | CA12 | O43570 | 1/20 | 0.32 |
| ▸ | CA1 | P00915 | 1/20 | 0.32 |
| ▸ | CA7 | P43166 | 1/20 | 0.32 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.32 |
| ▸ | APLNR | P35414 | 1/20 | 0.32 |
| ▸ | DPP8 | Q6V1X1 | 1/20 | 0.32 |
| ▸ | DPP9 | Q86TI2 | 1/20 | 0.32 |
| ▸ | GHSR | Q92847 | 1/20 | 0.31 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.31 |
| ▸ | NFKB2 | Q00653 | 1/20 | 0.31 |
| ▸ | RELA | Q04206 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13415253 | 1.00 | KMT2A (0.38) | KMT2AMEN1MAPK1CTSKALDH1A1 | |
| SCHEMBL15928515 | 0.82 | EPHX2 (0.34) | KMT2AMEN1MAPK1CTSKALDH1A1 | |
| SCHEMBL15928447 | 0.82 | EPHX2 (0.34) | KMT2AMEN1MAPK1CTSKALDH1A1 | |
| SCHEMBL15928475 | 0.82 | EPHX2 (0.34) | KMT2AMEN1MAPK1CTSKALDH1A1 | |
| SCHEMBL15928504 | 0.82 | EPHX2 (0.34) | KMT2AMEN1MAPK1CTSKALDH1A1 | |
| SCHEMBL22080250 | 0.81 | MEN1 (0.42) | KMT2AMEN1MAPK1CTSKCACNA1H | |
| SCHEMBL13360948 | 0.80 | KMT2A (0.41) | KMT2AMEN1MAPK1CTSKALDH1A1 | |
| SCHEMBL4383932 | 0.77 | KMT2A (0.37) | KMT2AMEN1MAPK1CTSKALDH1A1 | |
| SCHEMBL13302345 | 0.76 | MEN1 (0.38) | KMT2AMEN1MAPK1CTSKCACNA1H | |
| SCHEMBL8372247 | 0.76 | MEN1 (0.38) | KMT2AMEN1MAPK1CTSKCACNA1H |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-RE41356-E1 | Hepatitis C inhibitor tri-peptides | BOEHRINGER INGELHEIM CANADA LTD. (CA) | 2010-05-25 | — | — | US | disclosed |
| EP-2028186-A2 | Hepatitis C inhibitor tri-peptides | BOEHRINGER INGELHEIM (CANADA) LTD. (CA) | 2009-02-25 | — | — | EP | disclosed |
| US-RE40525-E1 | Hepatitis C inhibitor tri-peptides | BOEHRINGER INGELHEIM (CANADA) LTD. (CA) | 2008-09-30 | — | — | US | disclosed |