Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PIM1 | P11309 | 1/20 | 0.64 |
| ▸ | MAPT | P10636 | 4/20 | 0.62 |
| ▸ | DUSP3 | P51452 | 2/20 | 0.62 |
| ▸ | CTDSP1 | Q9GZU7 | 2/20 | 0.62 |
| ▸ | MCL1 | Q07820 | 1/20 | 0.62 |
| ▸ | APEX1 | P27695 | 4/20 | 0.57 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.52 |
| ▸ | HSD17B10 | Q99714 | 3/20 | 0.52 |
| ▸ | HPGD | P15428 | 3/20 | 0.52 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.52 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | MEN1 | O00255 | 2/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.51 |
| ▸ | PTPN7 | P35236 | 2/20 | 0.51 |
| ▸ | CACNA1B | Q00975 | 2/20 | 0.51 |
| ▸ | APBA1 | Q02410 | 2/20 | 0.51 |
| ▸ | PTPN22 | Q9Y2R2 | 2/20 | 0.51 |
| ▸ | PTPN12 | Q05209 | 1/20 | 0.51 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.49 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4551870 | 0.84 | PIM1 (0.63) | PIM1MAPTDUSP3CTDSP1MCL1 | |
| SCHEMBL4551871 | 0.84 | PIM1 (0.63) | PIM1MAPTDUSP3CTDSP1MCL1 | |
| SCHEMBL4551869 | 0.84 | PIM1 (0.63) | PIM1MAPTDUSP3CTDSP1MCL1 | |
| SCHEMBL16322180 | 0.80 | APEX1 (0.51) | PIM1MAPTDUSP3CTDSP1MCL1 | |
| SCHEMBL16322182 | 0.80 | APEX1 (0.51) | PIM1MAPTDUSP3CTDSP1MCL1 | |
| SCHEMBL16322183 | 0.80 | APEX1 (0.51) | PIM1MAPTDUSP3CTDSP1MCL1 | |
| SCHEMBL17830707 | 0.80 | APEX1 (0.61) | MAPTDUSP3CTDSP1MCL1APEX1 | |
| SCHEMBL13586997 | 0.79 | KAT2B (0.65) | MAPTDUSP3CTDSP1MCL1APEX1 | |
| SCHEMBL13362135 | 0.74 | APEX1 (0.52) | MAPTDUSP3CTDSP1MCL1APEX1 | |
| SCHEMBL17830703 | 0.73 | MEN1 (0.70) | MAPTDUSP3CTDSP1MCL1APEX1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8338464-B2 | Small molecule inhibitors of BCL6 | ALBERT EINSTEIN COLLEGE OF MEDICINE OF YESHIVA UNIVERSITY (US) | 2012-12-25 | — | — | US | disclosed |
| US-20100130564-A1 | SMALL MOLECULE INHIBITORS OF BCL6 | ALBERT EINSTEIN COLLEGE OF MEDICINE | 2010-05-27 | — | — | US | disclosed |
| WO-2008066887-A2 | SMALL MOLECULE INHIBITORS OF BCL6 | ALBERT EINSTEIN COLLEGE OF MEDICINE OF YESHIVA UNIVERSITY (US) | 2008-06-05 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100130564-A1 | SMALL MOLECULE INHIBITORS OF BCL6 | BCL6, BCL6B, BCOR | PIM1 2095/4885MAPT 4565/4885DUSP3 869/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.