⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL17804422 | 0.69 | — | — | |
| SCHEMBL1525606 | 0.68 | — | — | |
| SCHEMBL14299521 | 0.67 | — | — | |
| SCHEMBL142963 | 0.66 | — | — | |
| SCHEMBL7616159 | 0.65 | — | — | |
| SCHEMBL28958676 | 0.65 | — | — | |
| SCHEMBL12720216 | 0.62 | — | — | |
| Hydrochloric Acid SCHEMBL29199515 | 0.61 | — | — | |
| SCHEMBL742333 | 0.61 | — | — | |
| SCHEMBL762516 | 0.61 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010059575-A2 | COMBINATION THERAPY FOR THE TREATMENT OF CANCER | ISIS PHARMACEUTICALS, INC. (US) | 2010-05-27 | — | — | WO | disclosed |
| WO-2010059589-A1 | ANTICANCER COMBINATION COMPRISING DOCETAXEL AND AN ANTISENSE OLIGONUCLEOTIDE | ISIS PHARMACEUTICALS, INC. (US) | 2010-05-27 | — | — | WO | disclosed |