SCHEMBL1336775

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL1337642	0.92	MAPK1 (0.46)	MAPK1DPP4DPP8DPP9DPP7
	SCHEMBL4762437	0.89	MAPK1 (0.72)	MAPK1DPP4DPP8DPP9DPP7
	SCHEMBL4712216	0.86	MAPK1 (0.56)	MAPK1DPP4DPP8DPP9DPP7
	SCHEMBL10296223	0.85	MAPK1 (0.47)	MAPK1DPP4DPP8DPP9DPP7
	SCHEMBL2977256	0.84	MAPK1 (0.57)	MAPK1DPP4DPP8DPP9DPP7
	SCHEMBL2975661	0.84	MAPK1 (0.56)	MAPK1DPP4DPP8DPP9DPP7
	SCHEMBL2966970	0.84	MAPK1 (0.49)	MAPK1CREBBPBRD4NPC1HMOX1
	SCHEMBL10095067	0.84	BRD4 (0.67)	MAPK1CREBBPBRD4NPC1EP300
	SCHEMBL4030200	0.83	MAPK1 (0.48)	MAPK1DPP4DPP8DPP9DPP7
	SCHEMBL10211781	0.83	MAPK1 (0.55)	MAPK1CREBBPBRD4NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 19 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.