Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 14/20 | 0.53 |
| ▸ | PGR | P06401 | 13/20 | 0.53 |
| ▸ | NR3C2 | P08235 | 5/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.34 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | SLC6A4 | P31645 | 2/20 | 0.34 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.34 |
| ▸ | SHBG | P04278 | 1/20 | 0.34 |
| ▸ | POLB | P06746 | 1/20 | 0.34 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.34 |
| ▸ | ABCB11 | O95342 | 1/20 | 0.34 |
| ▸ | ESR1 | P03372 | 1/20 | 0.34 |
| ▸ | CYP19A1 | P11511 | 2/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4224696 | 0.84 | AR (0.54) | ARPGRNR3C2CYP3A4LMNA | |
| SCHEMBL13474810 | 0.82 | AR (0.57) | ARPGRNR3C2MEN1CYP3A4 | |
| SCHEMBL4107834 | 0.78 | CYP19A1 (0.55) | ARPGRNR3C2MEN1CYP3A4 | |
| SCHEMBL13372823 | 0.74 | AR (0.59) | ARPGRNR3C2MEN1CYP3A4 | |
| SCHEMBL6841944 | 0.74 | AR (0.55) | ARPGRNR3C2MEN1CYP3A4 | |
| SCHEMBL6841943 | 0.74 | AR (0.55) | ARPGRNR3C2MEN1CYP3A4 | |
| SCHEMBL28753933 | 0.73 | AR (0.49) | ARPGRNR3C2MEN1CYP3A4 | |
| SCHEMBL9138228 | 0.73 | AR (0.53) | ARPGRNR3C2MEN1CYP3A4 | |
| SCHEMBL9138223 | 0.73 | AR (0.53) | ARPGRNR3C2MEN1CYP3A4 | |
| SCHEMBL13809834 | 0.72 | AR (0.58) | ARPGRNR3C2CYP19A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2178899-B1 | 17BETA-CYANO-18A-HOMO-19-NOR-ANDROST-4-ENE DERIVATIVE, USE THEREOF AND MEDICAMENTS CONTAINING SAID DERIVATIVE | BAYER IP GMBH (DE) | 2012-10-24 | — | — | EP | claimed |
| EP-2178899-B1 | 17BETA-CYANO-18A-HOMO-19-NOR-ANDROST-4-ENE DERIVATIVE, USE THEREOF AND MEDICAMENTS CONTAINING SAID DERIVATIVE | BAYER IP GMBH (DE) | 2012-10-24 | — | — | EP | disclosed |