Predicted protein targets (top 10)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CSNK2A2 | P19784 | 1/20 | 0.49 |
| ▸ | KDR | P35968 | 1/20 | 0.49 |
| ▸ | CSNK2B | P67870 | 1/20 | 0.49 |
| ▸ | CSNK2A1 | P68400 | 1/20 | 0.49 |
| ▸ | FLT3 | P36888 | 10/20 | 0.45 |
| ▸ | HPSE | Q9Y251 | 1/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.40 |
| ▸ | DRD2 | P14416 | 1/20 | 0.40 |
| ▸ | DRD3 | P35462 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5952481 | 0.80 | CHEK1 (0.48) | FLT3HPSEKDM4EALDH1A1 | |
| SCHEMBL5953364 | 0.80 | HPSE (0.44) | HPSEKDM4EALDH1A1 | |
| SCHEMBL4089768 | 0.79 | HPSE (0.47) | HPSEKDM4EALDH1A1 | |
| SCHEMBL5951954 | 0.78 | PDE4D (0.50) | HPSEKDM4EALDH1A1 | |
| SCHEMBL13849191 | 0.77 | FLT3 (0.65) | FLT3KDM4E | |
| SCHEMBL13849202 | 0.76 | FLT3 (0.61) | FLT3 | |
| SCHEMBL4096535 | 0.75 | HPSE (0.41) | FLT3HPSEKDM4EALDH1A1 | |
| SCHEMBL13849221 | 0.75 | CHEK1 (0.42) | FLT3HPSEKDM4EALDH1A1 | |
| SCHEMBL5952720 | 0.75 | HPSE (0.42) | FLT3HPSEKDM4EALDH1A1 | |
| SCHEMBL13849263 | 0.74 | FLT3 (0.56) | FLT3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8288425-B2 | Benzimidazoles | AVENTIS PHARMACEUTICALS INC. (US) | 2012-10-16 | — | — | US | disclosed |