Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CDK5 | Q00535 | 5/20 | 0.37 |
| ▸ | CDK5R1 | Q15078 | 5/20 | 0.37 |
| ▸ | CCNB2 | O95067 | 1/20 | 0.36 |
| ▸ | CDK1 | P06493 | 1/20 | 0.36 |
| ▸ | CCNB1 | P14635 | 1/20 | 0.36 |
| ▸ | CCNB3 | Q8WWL7 | 1/20 | 0.36 |
| ▸ | HDAC1 | Q13547 | 2/20 | 0.34 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.34 |
| ▸ | RET | P07949 | 1/20 | 0.33 |
| ▸ | KDR | P35968 | 1/20 | 0.33 |
| ▸ | MDM2 | Q00987 | 1/20 | 0.32 |
| ▸ | IDO1 | P14902 | 1/20 | 0.32 |
| ▸ | HDAC3 | O15379 | 1/20 | 0.32 |
| ▸ | HDAC4 | P56524 | 1/20 | 0.32 |
| ▸ | HDAC7 | Q8WUI4 | 1/20 | 0.32 |
| ▸ | HDAC2 | Q92769 | 1/20 | 0.32 |
| ▸ | HDAC10 | Q969S8 | 1/20 | 0.32 |
| ▸ | HDAC11 | Q96DB2 | 1/20 | 0.32 |
| ▸ | HDAC8 | Q9BY41 | 1/20 | 0.32 |
| ▸ | HDAC9 | Q9UKV0 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13375794 | 0.90 | CDK5 (0.39) | CDK5CDK5R1CCNB2CDK1CCNB1 | |
| SCHEMBL16417867 | 0.87 | CDK5 (0.36) | CDK5CDK5R1CCNB2CDK1CCNB1 | |
| SCHEMBL13897557 | 0.84 | HDAC1 (0.38) | CDK5CDK5R1CCNB2CDK1CCNB1 | |
| SCHEMBL16417876 | 0.83 | CDK5 (0.35) | CDK5CDK5R1CCNB2CDK1CCNB1 | |
| SCHEMBL13375795 | 0.80 | ADORA1 (0.40) | ADORA1 | |
| SCHEMBL12724727 | 0.79 | TYMP (0.46) | ADORA1 | |
| SCHEMBL13930532 | 0.79 | TYMP (0.46) | ADORA1 | |
| SCHEMBL13897165 | 0.79 | TYMP (0.46) | ADORA1 | |
| SCHEMBL13952071 | 0.77 | CDK5 (0.35) | CDK5CDK5R1CCNB2CDK1CCNB1 | |
| SCHEMBL21284196 | 0.74 | CCNB2 (0.39) | CDK5CDK5R1CCNB2CDK1CCNB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-8288516-B2 | Functional molecule, functional molecule synthesizing amidite and target substance analysis method | FUJITSU LIMITED (JP) | 2012-10-16 | — | — | US | disclosed |