Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TP53 | P04637 | 3/20 | 0.44 |
| ▸ | LMNA | P02545 | 5/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | ENPP2 | Q13822 | 2/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.38 |
| ▸ | MAPT | P10636 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL13376532 | 0.97 | TP53 (0.47) | TP53LMNAPOLBENPP2KDM4E | |
| SCHEMBL13376528 | 0.93 | TP53 (0.48) | TP53LMNAPOLBENPP2 | |
| SCHEMBL13376501 | 0.93 | TP53 (0.47) | TP53LMNAPOLBENPP2 | |
| SCHEMBL3287749 | 0.90 | TP53 (0.44) | TP53LMNAPOLBENPP2 | |
| SCHEMBL13376520 | 0.88 | TP53 (0.44) | TP53LMNAPOLBENPP2 | |
| SCHEMBL13376497 | 0.88 | TP53 (0.46) | TP53LMNAPOLBENPP2MAPT | |
| SCHEMBL13376495 | 0.88 | TP53 (0.46) | TP53LMNAPOLBENPP2 | |
| SCHEMBL13376548 | 0.87 | TP53 (0.45) | TP53LMNAPOLBENPP2MAPT | |
| SCHEMBL3285184 | 0.87 | TP53 (0.47) | TP53LMNAPOLBENPP2 | |
| SCHEMBL13376526 | 0.86 | TP53 (0.44) | TP53LMNAPOLBENPP2MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1858890-B1 | NOVEL ANTITHROMBOTIC SUBSTITUTED PYRROLIDINONES, THE PRODUCTION AND USE THEREOF IN THE FORM OF MEDICAMENTS | BOEHRINGER INGELHEIM PHARMA (DE) | 2010-04-14 | — | — | EP | disclosed |