Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK2 | Q15119 | 2/20 | 0.59 |
| ▸ | PTPRC | P08575 | 2/20 | 0.50 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.50 |
| ▸ | CHEK1 | O14757 | 1/20 | 0.47 |
| ▸ | HTR7 | P34969 | 3/20 | 0.43 |
| ▸ | ALOX5AP | P20292 | 1/20 | 0.42 |
| ▸ | FEN1 | P39748 | 1/20 | 0.42 |
| ▸ | PGR | P06401 | 3/20 | 0.41 |
| ▸ | NR3C1 | P04150 | 2/20 | 0.41 |
| ▸ | PIK3R1 | P27986 | 1/20 | 0.40 |
| ▸ | PIK3CA | P42336 | 1/20 | 0.40 |
| ▸ | ADORA1 | P30542 | 1/20 | 0.40 |
| ▸ | TNKS2 | Q9H2K2 | 1/20 | 0.40 |
| ▸ | AR | P10275 | 1/20 | 0.40 |
| ▸ | DHFR | P00374 | 1/20 | 0.40 |
| ▸ | MAP4K4 | O95819 | 1/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.39 |
| ▸ | HPGD | P15428 | 1/20 | 0.39 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2129264 | 0.84 | PDK2 (0.44) | PDK2 | |
| SCHEMBL12393756 | 0.82 | PDK2 (0.59) | PDK2HPGDSMN1; SMN2 | |
| SCHEMBL27968523 | 0.80 | PDK2 (0.39) | PDK2PGR | |
| SCHEMBL20081106 | 0.80 | PDK2 (0.63) | PDK2PTPRCPTPN1CHEK1HTR7 | |
| SCHEMBL28055711 | 0.80 | PDK2 (0.51) | PDK2PGRSMN1; SMN2 | |
| SCHEMBL12056905 | 0.79 | PDK2 (0.49) | PDK2 | |
| SCHEMBL19153046 | 0.79 | ESR2 (0.42) | PDK2ALOX5APFEN1PGRAR | |
| SCHEMBL13378326 | 0.79 | PDK2 (0.38) | PDK2ALDH1A1SMN1; SMN2 | |
| SCHEMBL6683913 | 0.77 | PDK2 (0.38) | PDK2PGR | |
| SCHEMBL10153158 | 0.77 | PDK2 (0.47) | PDK2ALDH1A1HPGDSMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2010036025-A2 | TRANSITION METAL CATALYTIC SYSTEMS AND METHODS FOR PREPARING ETHYLENE HOMOPOLYMERS OR COPOLYMERS OF ETHYLENE AND α- OLEFINS USING THE SAME. | SK ENERGY CO., LTD. (KR) | 2010-04-01 | — | — | WO | disclosed |