Predicted protein targets (top 6)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPY1R | P25929 | 1/20 | 0.69 |
| ▸ | HTT | P42858 | 1/20 | 0.69 |
| ▸ | NPY2R | P49146 | 1/20 | 0.69 |
| ▸ | CNR2 | P34972 | 18/20 | 0.57 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.52 |
| ▸ | CNR1 | P21554 | 6/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2888553 | 1.00 | NPY1R (0.69) | NPY1RHTTNPY2RCNR2KDM4E | |
| SCHEMBL2890670 | 0.82 | NPY1R (0.82) | NPY1RHTTNPY2RCNR2KDM4E | |
| SCHEMBL13379183 | 0.82 | NPY1R (0.82) | NPY1RHTTNPY2RCNR2KDM4E | |
| SCHEMBL13378438 | 0.81 | NPY1R (0.65) | NPY1RHTTNPY2RCNR2KDM4E | |
| SCHEMBL2888516 | 0.80 | NPY1R (0.64) | NPY1RHTTNPY2RCNR2KDM4E | |
| SCHEMBL13379182 | 0.80 | NPY1R (0.77) | NPY1RHTTNPY2RCNR2KDM4E | |
| SCHEMBL2889647 | 0.80 | NPY1R (0.77) | NPY1RHTTNPY2RCNR2KDM4E | |
| SCHEMBL13227808 | 0.79 | NPY1R (0.72) | NPY1RHTTNPY2RCNR2KDM4E | |
| SCHEMBL13379189 | 0.77 | CNR2 (0.61) | NPY1RHTTNPY2RCNR2CNR1 | |
| SCHEMBL2882548 | 0.77 | CNR2 (0.61) | NPY1RHTTNPY2RCNR2CNR1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20100099673-A1 | DECAHYDROQUINOLINE ANALOGS AS CB2 RECEPTOR MODULATORS, USEFUL IN THE TREATMENT OF PAIN, RESPIRATORY AND NON-RESPIRATORY DISEASES | MERCK SHARP & DOHME CORP. | 2010-04-22 | — | — | US | disclosed |
| US-20100099673-A1 | DECAHYDROQUINOLINE ANALOGS AS CB2 RECEPTOR MODULATORS, USEFUL IN THE TREATMENT OF PAIN, RESPIRATORY AND NON-RESPIRATORY DISEASES | MERCK SHARP & DOHME CORP. | 2010-04-22 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100099673-A1 | DECAHYDROQUINOLINE ANALOGS AS CB2 RECEPTOR MODULATORS, USEFUL IN THE TREATMENT OF PAIN, RESPIRATORY AND NON-RESPIRATORY DISEASES | CNR2, CNR1, TRPV1 | NPY1R 107/4885HTT 2944/4885NPY2R 63/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.