⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL4329317 | 0.69 | — | — | |
| SCHEMBL17987080 | 0.65 | — | — | |
| SCHEMBL15934156 | 0.65 | — | — | |
| SCHEMBL1698769 | 0.64 | CHRM2 (0.32) | — | |
| SCHEMBL1698770 | 0.64 | CHRM2 (0.32) | — | |
| SCHEMBL23194386 | 0.62 | TSHR (0.31) | — | |
| SCHEMBL25543300 | 0.61 | CHRM2 (0.33) | — | |
| SCHEMBL21709965 | 0.61 | CHRM2 (0.36) | — | |
| SCHEMBL23205840 | 0.61 | CHRM2 (0.33) | — | |
| SCHEMBL15932140 | 0.60 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20230357820-A1 | TEST METHOD FOR MILD COGNITIVE IMPAIRMENT, TEST REAGENT FOR MILD COGNITIVE IMPAIRMENT, AND METHOD FOR SCREENING THERAPEUTIC CANDIDATE SUBSTANCES FOR MILD COGNITIVE IMPAIRMENT | BIORADICAL RESEARCH INSTITUTE CORP. (JP) | 2023-11-09 | — | — | US | disclosed |
| US-7700778-B2 | Acylated piperidine derivatives as melanocortin-4 receptor agonists | MERCK SHARP & DOHME CORP. (US) | 2010-04-20 | — | — | US | disclosed |