⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6221243 | 0.83 | SMN1; SMN2 (0.34) | — | |
| SCHEMBL10453358 | 0.81 | SMN1; SMN2 (0.33) | — | |
| SCHEMBL23462764 | 0.75 | — | — | |
| SCHEMBL25417178 | 0.75 | — | — | |
| SCHEMBL2080511 | 0.75 | — | — | |
| SCHEMBL1876188 | 0.73 | CRBN (0.32) | — | |
| SCHEMBL6304043 | 0.73 | SMN1; SMN2 (0.36) | — | |
| SCHEMBL1937977 | 0.73 | — | — | |
| SCHEMBL3615148 | 0.71 | SMN1; SMN2 (0.50) | — | |
| SCHEMBL12490737 | 0.69 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 216 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-114127057-A | Phenylaminopyrimidine amide autophagy inhibitors and methods of use thereof | 德西费拉制药有限责任公司 | 2022-03-01 | — | — | CN | claimed |
| CN-114072397-A | Heteroaryl aminopyrimidine amide autophagy inhibitors and methods of use thereof | 德西费拉制药有限责任公司 | 2022-02-18 | — | — | CN | claimed |
| US-20200157280-A1 | POLYAMIDES BASED ON AMINOALKYLPIPERAZINE OR AMINOARYLPIPERAZINE FOR HOT-MELT ADHESIVES | ARKEMA FRANCE (FR) | 2020-05-21 | — | — | US | claimed |
| WO-2018175386-A1 | POLYAMIDE COMPOSITIONS COMPRISING A THERMOPLASTIC POLYMER | THE UNIVERSITY OF MASSACHUSETTS (US) | 2018-09-27 | — | — | WO | claimed |
| WO-2018175384-A1 | CYRSTALLINE, POROUS POLYAMIDE COMPOSITIONS | THE UNIVERSITY OF MASSACHUSETTS (US) | 2018-09-27 | — | — | WO | claimed |
| EP-2920172-A1 | PURINE INHIBITORS OF HUMAN PHOSPHATIDYLINOSITOL 3-KINASE DELTA | Merck Sharp & Dohme Corp. (US) | 2015-09-23 | — | — | EP | claimed |
| WO-2014075393-A1 | PURINE INHIBITORS OF HUMAN PHOSPHATIDYLINOSITOL 3-KINASE DELTA | MERCK SHARP & DOHME CORP. (US) | 2014-05-22 | — | — | WO | claimed |
| US-7342027-B2 | 1-phenylpiperidin-3-one derivatives and processes for the preparation thereof | YUHAN CORPORATION (KR) | 2008-03-11 | — | — | US | claimed |
| WO-2006095094-A1 | NANOSTRUCTURED DUAL-PHASE MATERIAL COMPRISING A POLYAMIDE MATRIX AND ELASTOMERIC NODULES | CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (FR) | 2006-09-14 | — | — | WO | claimed |
| US-20050234057-A1 | 1-Phenylpiperidin-3-one derivatives and processes for the preparation thereof | DONG-A PHARMACEUTICAL CO., LTD. (KR) | 2005-10-20 | — | — | US | claimed |
| WO-2004011457-A1 | 1-PHENYLPIPERIDIN-3-ONE DERIVATIVES AND PROCESSES FOR THE PREPARATION THEREOF | YUHAN CORPORATION (KR) | 2004-02-05 | — | — | WO | claimed |
| US-6579965-B2 | Process for the anionic polymerization of lactams | ATOFINA (FR) | 2003-06-17 | — | — | US | claimed |
| US-6228976-B1 | HEAT TREATMENT OF ANIONICALLY POLYMERIZED POLYLACTAMS TO PROVIDE A UNIMODAL DISTRIBUTION OF MOLAR MASSES; VISCOSITY STABILIZATION | ELF ATOCHEM S.A. (FR) | 2001-05-08 | — | — | US | claimed |
| CN-122095025-A | Polyamide composition and molded article | — | 2026-05-26 | — | — | CN | disclosed |
| EP-4050056-B1 | REINFORCED RESIN COMPOSITION, MOLDED PRODUCT, AND METHOD OF IMPROVING TENSILE STRENGTH AT ELEVATED TEMPERATURES | ASAHI CHEMICAL IND (JP) | 2026-04-01 | — | — | EP | disclosed |
| US-12441065-B2 | Formed article, welding method, and method of manufacturing formed article | ASAHI KASEI KABUSHIKI KAISHA (JP) | 2025-10-14 | — | — | US | disclosed |
| EP-0800516-A1 | FIBRINOGEN RECEPTOR ANTAGONISTS HAVING SUBSTITUTED (b)-AMINO ACID RESIDUES AND PHARMACEUTICAL COMPOSITIONS COMPRISING THE SAME | NIPPON STEEL CORPORATION (JP) | 1997-10-15 | — | — | EP | disclosed |
| WO-1996020172-A1 | FIBRINOGEN RECEPTOR ANTAGONISTS HAVING SUBSTITUTED β-AMINO ACID RESIDUES AND PHARMACEUTICAL COMPOSITIONS COMPRISING THE SAME | NIPPON STEEL CORPORATION (JP) | 1996-07-04 | — | — | WO | disclosed |
| US-4683303-A | Reduction process for the preparation of 4-unsubstituted azetidin-2-ones | PFAENDLER HANS R (DE) | 1987-07-28 | — | — | US | disclosed |
| US-4297454-A | Manufacture of a block copolymer containing a polyetheramide and a polylactam | SUNTECH, INC. (US) | 1981-10-27 | — | — | US | disclosed |